Evidence map›Paper›PMID 34722652›Full record

ArticleFrontiers in cardiovascular medicine2021

Blockade of Exosome Release Suppresses Atrial Fibrillation by Alleviating Atrial Fibrosis in Canines With Prolonged Atrial Pacing.

Yajun Yao, Shanqing He, Youcheng Wang, Zhen Cao, Dishiwen Liu, Yuntao Fu, Huiyu Chen, Xi Wang, Qingyan Zhao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Circulating Extracellular Vesicles DownregulateJournal of clinical medicine · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Extracellular Vesicles in Atrial Fibrillation-State of the Art.International journal of molecular sciences · 2022
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yajun YaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Shanqing HeDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Youcheng WangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhen CaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Dishiwen LiuDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Yuntao FuDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Huiyu ChenDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Xi WangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Qingyan ZhaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Renmin Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atrial fibrillationcanineexosomesfibrosisMiR-21-5pTIMP3

Identifiers

PMID34722652
PMCPMC8553970
OpenAlexW3206730496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.