Evidence map›Paper›PMID 34722619›Full record

ArticleFrontiers in surgery2021

Upfront Brain Treatments Followed by Lung Surgery Improves Survival for Stage IV Non-small Cell Lung Cancer Patients With Brain Metastases: A Large Cohort Analysis.

Xiaopeng He, Shen Yin, Hongyu Liu, Rong Lu, Kemp Kernstine, David E Gerber, Yang Xie, Donghan M Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xiaopeng HeDepartment of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Shen YinQuantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Hongyu LiuQuantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Rong LuQuantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Kemp KernstineDepartment of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, United States.
David E GerberDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Yang XieQuantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Donghan M YangQuantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States.
The University of Texas Southwestern Medical Center · USShandong Provincial Hospital · CNSouthern Methodist University · US

Funding

UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HEYMACH, JOHN V. · 1996 to 2024
$57.4M
Integrative Analysis to Identify Therapeutic Targets for Lung CancerR01CA172211 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI XIAO, GUANGHUA · 2013 to 2017
$1.6M
Integrative Analysis to Identify Regulation Targets of RNA-Binding ProteinsR01GM115473 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI XIE, YANG · 2016 to 2019
$1.3M
Development of New Cancer Treatments and InvestigatorsK24CA201543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GERBER, DAVID ERIC · 2016 to 2020
$737k
NCI NIH HHS K24 CA201543NCI NIH HHS P50 CA070907NCI NIH HHS R01 CA172211NIGMS NIH HHS R01 GM115473
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain metastasesNational Cancer Databasenon-small cell lung cancersurgerytreatment sequencing

Identifiers

PMID34722619
PMCPMC8549861
OpenAlexW3206411643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.