Evidence map›Paper›PMID 34722501›Full record

ArticleFrontiers in cell and developmental biology2021

Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis.

Shuang Wu, Kai Chen, Tao Xu, Ke Ma, Lei Gao, Cong Fu, Wenjuan Zhang, Changbin Jing, Chunguang Ren, Min Deng and 4 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Shuang WuShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Kai ChenShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Tao XuShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Ke MaShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Lei GaoShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Cong FuShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Wenjuan ZhangShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Changbin JingShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Chunguang RenShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Min DengShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Yi ChenState Key Laboratory for Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi ZhouStem Cell Program, Hematology/Oncology Program at Children's Hospital Boston, Harvard Medical School, Boston, MA, United States.
Weijun PanShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Xiaoe JiaShanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China.
Chinese Academy of Sciences · CNShanghai Institute of Nutrition and Health · CNHarvard University · USShanghai Institute of Hematology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vertebrate erythropoiesis involves nuclear and chromatin condensation at the early stages of terminal differentiation, which is a unique process to distinguish mature erythrocytes from erythroblasts. However, the underlying mechanisms of chromatin condensation during erythrocyte maturation remain elusive. Here, we reported a novel zebrafish mutant

Indexed as

chromatin condensationerythrocyteserythroid maturationTprzebrafish

Identifiers

PMID34722501
PMCPMC8548687
OpenAlexW3207322201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.