Evidence map›Paper›PMID 34722478›Full record

ArticleFrontiers in bioengineering and biotechnology2021

An NIR-II Responsive Nanoplatform for Cancer Photothermal and Oxidative Stress Therapy.

Bin Huang, Yuanpeng Huang, Han Han, Qiuyue Ge, Dongliang Yang, Yanling Hu, Meng Ding, Yanqing Su, Yanbin He, Jinjun Shao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Bin HuangAcademy of Integrative Medicine of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Yuanpeng HuangXiamen Hospital of Traditional Chinese Medicine, Xiamen, China.
Han HanSchool of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), Nanjing, China.
Qiuyue GeSchool of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), Nanjing, China.
Dongliang YangSchool of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), Nanjing, China.
Yanling HuSchool of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), Nanjing, China.
Meng DingNanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Yanqing SuDepartment of Pharmacy, Xiamen Children's Hospital, Xiamen, China.
Yanbin HeAcademy of Integrative Medicine of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Jinjun ShaoXiamen Hospital of Traditional Chinese Medicine, Xiamen, China.
Jianfeng ChuAcademy of Integrative Medicine of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Nanjing Tech University · CNFujian University of Traditional Chinese Medicine · CNUnion Hospital · CNChildren’s Hospital of Fudan University Xiamen Branch · CNNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemodynamic therapy as an emerging therapeutic strategy has been implemented for oncotherapy. However, the reactive oxygen species can be counteracted by the exorbitant glutathione (GSH) produced by the tumor cells before exerting the antitumor effect. Herein, borneol (NB) serving as a monoterpenoid sensitizer, and copper sulfide (CuS NPs) as an NIR-II photothermal agent were loaded in a thermo-responsive vehicle (NB/CuS@PCM NPs). Under 1,060-nm laser irradiation, the hyperthermia produced by CuS NPs can be used for photothermal therapy and melt the phase change material for drug delivery. In the acidity microenvironment, the CuS NPs released from NB/CuS@PCM NPs could degrade to Cu

Indexed as

chemodynamic therapydrug deliveryphase change materialphotothermal ablation therapyresponsive nanomaterial

Identifiers

PMID34722478
PMCPMC8553991
OpenAlexW3207873807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.