Evidence map›Paper›PMID 34722329›Full record

ArticleFrontiers in cellular and infection microbiology2021

The Effects of Chinese Medicine QRD, Antibiotics, and Probiotics on Therapy and Gut Microbiota in Septic Rats.

Huiling Cao, Chunhui Zong, Wenkui Dai, Qiaoying Gao, Donghua Li, Xianzhong Wu, Dongfang Li, Yi-Wei Tang, Shangwei Wu

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huiling CaoDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Chunhui ZongInstitute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.
Wenkui DaiDepartment of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China.
Qiaoying GaoInstitute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.
Donghua LiInstitute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.
Xianzhong WuInstitute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.
Dongfang LiDepartment of Microbial Research, WeHealthGene Institute, Shenzhen, China.
Yi-Wei TangDepartment of Medical Affairs, Danaher Diagnostic Platform/Cepheid (China), Shanghai, China.
Shangwei WuInstitute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a common and often treacherous medical emergency with a high mortality and long-term complications in survivors. Though antibiotic therapy can reduce death rate of sepsis significantly, it impairs gut microbiota (GM), which play imperative roles in human health. In this study, we compared the therapeutic effects of antibiotics, probiotics, and Chinese medicine QRD on the survival rates of septic model and observed the GM characteristics of experimental rats

Indexed as

Gastrointestinal MicrobiomeProbioticsSepsisAnimalsAnti-Bacterial AgentsMedicine, Chinese TraditionalRatsRNA, Ribosomal, 16SAnti-Bacterial AgentsRNA, Ribosomal, 16Santibioticsgut microbiotaprobioticsQing Re Jie Du Fang Decoctionsepsis

Identifiers

PMID34722329
PMCPMC8552555

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.