Evidence map›Paper›PMID 34722186›Full record

ArticleJournal of clinical and translational hepatology2021

Development of a Novel Endovascular Brachytherapy Stent: A Proof-of-concept Study.

Nan Du, Jingqin Ma, Zihan Zhang, Yongjie Zhou, Minjie Yang, Wen Zhang, Jianjun Luo, Zhiping Yan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nan DuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-8881-2625
Jingqin MaDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-8755-3411
Zihan ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-0957-9701
Yongjie ZhouDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-9578-3922
Minjie YangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-6491-1300
Wen ZhangDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-2301-147X
Jianjun LuoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-4942-0439
Zhiping YanDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-7907-435X
Fudan University · CNShanghai Institute of Hematology · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEndovascular implantation of iodine-125 (

methodsAn EVB-Stent was implanted into the main portal vein (MPV) in a live porcine model via the percutaneous transhepatic route. Blood samples were collected and tested before and after operation, as well as before euthanasia. Single-photon emission computed tomography (SPECT) combined with CT (SPECT/CT) scan were performed directly after operation and CT scan was performed 2 months after implantation. After the CT scan was performed, all animals were euthanized and histologically examined.

resultsThe novel stent was successfully positioned in all six pigs. No deterioration of liver function was observed during the 2-month follow-up period. SPECT/CT revealed the uniform distribution of radiation around the seeds strand, and the hottest spot was near the center of the MPV. The patency of the stented MPV was confirmed using CT scans. The tissue-accumulated absorbed dose was 31,822.11 mGy at 10 mm transversely away from the midpoint of the

conclusionsA liver porcine model was used to demonstrate that the transhepatic placement of a novel endovascular brachytherapy stent, EVB-Stent, is both technically feasible and safe.

Indexed as

BrachytherapyIodine-125 seeds strandPortal vein tumorStentTumor thrombus

Identifiers

PMID34722186
PMCPMC8516836
OpenAlexW3181539072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.