Evidence map›Paper›PMID 34721826›Full record

ArticleJournal of healthcare engineering2021

Clinical and Imaging Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Morphine Dependence Through mGluR5/TDP43/NR2B Pathway.

Xin Li, Congyan Li, Jia'nan Yu, Qing Ji, Wei Wang, Ying Peng, Xiaofeng Zhu, Jiguang Liu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Journal of healthcare engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xin LiSchool of Basic Medicine, Jiamusi University, Jiamusi 154000, Heilongjiang, China.ORCID 0000-0003-0043-0943
Congyan LiDepartment of Neurology, The First Affiliated Hospital of Jiamusi University, Jiamusi 154000, Heilongjiang, China.
Jia'nan YuDepartment of Neurology, The First Affiliated Hospital of Jiamusi University, Jiamusi 154000, Heilongjiang, China.
Qing JiGraduate School, Jiamusi University, Jiamusi 154000, Heilongjiang, China.
Wei WangGraduate School, Jiamusi University, Jiamusi 154000, Heilongjiang, China.
Ying PengDepartment of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510000, Guangdong, China.
Xiaofeng ZhuMudanjiang Medical University, Mudanjiang 157000, Heilongjiang, China.
Jiguang LiuSchool of Basic Medicine, Jiamusi University, Jiamusi 154000, Heilongjiang, China.ORCID 0000-0003-4956-175X
Jiamusi University · CNFirst Affiliated Hospital of Jiamusi University · CNMudanjiang Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morphine is tolerable after long-term use. After long-term use, it will have a great impact on the human body, and the treatment effect is not good. In recent years, the continuous development of repetitive transcranial magnetic stimulation (rTMS) treatment technology has made a treatment. Drug-resistant morphine dependence has a breakthrough. In this article, to study the effect of repeated transcranial magnetic stimulation in the treatment of morphine dependence through mGluR5/TDP43/NR2B pathway, experiments were carried out on rats to compare the changes in the images of rats after different periods of morphine use and their effects on morphine withdrawal. During the period, the performance of rats provides a reference for repeated transcranial stimulation to treat morphine dependence. According to the experimental results, after stopping morphine, withdrawal from the rats, irritable acts, and patience diminished. This is a decrease of more than 50% in comparison with the one of the normal group. There was a different degree of variability in the treatment images of mGluR5/TDP43 and so on after rTMS treatment, and the changes were large. These reductions in detoxification responses in rodents suggest that rTMS serves an instrumental role in the prevention and treatment of phosphorylation related to morphine dependence.

Indexed as

Morphine DependenceSubstance-Related DisordersAnimalsRatsTranscranial Magnetic Stimulation

Identifiers

PMID34721826
PMCPMC8550831
OpenAlexW3205391164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.