Evidence map›Paper›PMID 34721736›Full record

ArticleDisease markers2021

The Metabolome of Carbapenem-Resistant Klebsiella pneumoniae Infection in Plasma.

Zhongwei Wen, Mei Liu, Dong Rui, Xiaoxiao Liao, Rui Su, Zhenming Tang, Zhineng Wen, Zhougui Ling

Abstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Profiling of Volatile Metabolites ofInternational journal of molecular sciences · 2025
    Article
  4. LC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacterales.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. GC-MS profiling of volatile metabolites produced byFrontiers in molecular biosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhongwei WenDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Mei LiuDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Dong RuiDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Xiaoxiao LiaoDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Rui SuDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Zhenming TangDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Zhineng WenDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.
Zhougui LingDepartment of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Guangxi Medical University, No. 156 Heping Road, Liuzhou 545005, Guangxi Province, China.ORCID https://orcid.org/0000-0001-5174-5262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimCarbapenem-resistant

methodsIn this study, we comprehensively profile the metabolites of 20 CR-Kp-positive and 18 CR-Kp-negative patients in plasma by using 2D gas chromatography-time-of-flight mass spectrometry (GC×GC-TOFMS).

resultsWe identified 58 metabolites that were carbapenem-resistant

conclusionsOur study provides valuable data to serve as potential targets for developing therapies against CR-Kp infection.

Indexed as

Drug Resistance, BacterialMetabolomeAdultAgedBiomarkersCarbapenemsCase-Control StudiesChinaFemaleFollow-Up StudiesHumansKlebsiella InfectionsKlebsiella pneumoniaeMaleMiddle AgedPrognosisBiomarkersCarbapenems

Identifiers

PMID34721736
PMCPMC8556109

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.