Evidence map›Paper›PMID 34721669›Full record

ReviewEuropean cardiology2021

Transcatheter Aortic Valve Implantation and Subclinical and Clinical Leaflet Thrombosis: Multimodality Imaging for Diagnosis and Risk Stratification.

María Martín, Javier Cuevas, Helena Cigarrán, Juan Calvo, César Morís

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Prediction model for leaflet thrombosis in patients undergoing transcatheter aortic valve implantation: the EFFORT study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Observational
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

María MartínCardiology Department, University Hospital of Asturias Oviedo, Asturias, Spain.
Javier CuevasCardiology Department, University Hospital of Asturias Oviedo, Asturias, Spain.
Helena CigarránRadiology Department, University Hospital of Asturias Oviedo, Asturias, Spain.
Juan CalvoRadiology Department, University Hospital of Asturias Oviedo, Asturias, Spain.
César MorísCardiology Department, University Hospital of Asturias Oviedo, Asturias, Spain.
Hospital Universitario Central de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the phenomenon of subclinical leaflet thrombosis (SLT) in patients who have undergone transcatheter aortic valve implantation has become increasingly relevant. Hypo-attenuating leaflet thickening and hypo-attenuation affecting motion diagnosed by CT are the hallmarks of SLT, and their incidence varies depending on the intensity of screening. Whether these phenomena are a surrogate for leaflet thrombosis reducing valve durability and increasing the risk of stroke is still a matter of debate. Uncertainty remains over the optimal antithrombotic therapy after TAVI and the best treatment strategy is still not confirmed. Ongoing and future trials will provide more evidence about the best strategy for the prevention and treatment of SLT.

Indexed as

cardiac CThypo-attenuating leaflet thickeninghypo-attenuation affecting motionsubclinical thrombosisTranscatheter aortic valve implantation

Identifiers

PMID34721669
PMCPMC8546909
OpenAlexW3201967249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.