Evidence map›Paper›PMID 34721666›Full record

ReviewInterventional cardiology (London, England)2021

Factors Influencing Stent Failure in Chronic Total Occlusion Coronary Intervention.

Kalaivani Mahadevan, Claudia Cosgrove, Julian W Strange

Open access · goldAbstract readReview
In one paragraph

Review in Interventional cardiology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Clinical outcomes of drug-coated balloonsCardiovascular diagnosis and therapy · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Predictors of long-term adverse outcomes after successful chronic total occlusion intervention: physiology or morphology?Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kalaivani MahadevanDepartment of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust Bristol, UK.
Claudia CosgroveDepartment of Cardiology, St George's University NHS Trust London, UK.
Julian W StrangeDepartment of Cardiology, University Hospitals Bristol and Weston NHS Foundation Trust Bristol, UK.
University Hospitals Bristol NHS Foundation Trust · GBSt George’s University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stent failure remains one of the greatest challenges for interventional cardiologists. Despite the evolution to superior second- and third-generation drug-eluting stent designs, increasing use of intracoronary imaging and the adoption of more potent antiplatelet regimens, registries continue to demonstrate a prevalence of stent failure or target lesion revascularisation of 15-20%. Predisposition to stent failure is consistent across both chronic total occlusion (CTO) and non-CTO populations and includes patient-, lesion- and procedure-related factors. However, histological and pathophysiological properties specific to CTOs, alongside complex strategies to treat these lesions, may potentially render percutaneous coronary interventions in this cohort more vulnerable to failure. Prevention requires recognition and mitigation of the precipitants of stent failure, optimisation of interventional techniques, including image-guided precision percutaneous coronary intervention, and aggressive modification of a patient's cardiovascular risk factors. Management of stent failure in the CTO population is technically challenging and itself begets recurrence. We aim to provide a comprehensive review of factors influencing stent failure in the CTO population and strategies to attenuate these.

Indexed as

chronic total occlusionin-stent restenosisStent failurestenting strategystent thrombosis

Identifiers

PMID34721666
PMCPMC8532005
OpenAlexW3206484276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.