Evidence map›Paper›PMID 34721536›Full record

ArticleFrontiers in genetics2021

A Novel Homozygous Missense Mutation in the Zinc Finger DNA Binding Domain of GLI1 Causes Recessive Post-Axial Polydactyly.

Muhammad Umair, Farooq Ahmad, Saeed Ahmad, Qamre Alam, Mohd Rehan, Amany I Alqosaibi, Mashael M Alnamshan, Misbahuddin M Rafeeq, Shahnaz Haque, Ziaullah M Sain and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Identification of a NovelMolecular syndromology · 2023
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  3. Article
  4. Deleterious Rare Mutations ofFrontiers in cardiovascular medicine · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Muhammad UmairMedical Genomics Research Department, King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for Health Science, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia.
Farooq AhmadDepartment of Chemistry, Women University Swabi, Swabi, Pakistan.
Saeed AhmadConsultant Orthopedic Surgeon, Capital Hospital Islamabad, Islamabad, Pakistan.
Qamre AlamMedical Genomics Research Department, King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for Health Science, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia.
Mohd RehanKing Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Amany I AlqosaibiDepartment of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mashael M AlnamshanDepartment of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Misbahuddin M RafeeqDepartment of Pharmacology, Faculty of Medicine, Rabigh, King Abduaziz University, Jeddah, Saudi Arabia.
Shahnaz HaqueDepartment of Pharmacology, Faculty of Medicine, Rabigh, King Abduaziz University, Jeddah, Saudi Arabia.
Ziaullah M SainDepartment of Microbiology, Faculty of Medicine, Rabigh, King Abduaziz University, Jeddah, Saudi Arabia.
Muhammad IsmailDepartment of Chemistry, Women University Swabi, Swabi, Pakistan.
Majid AlfadhelMedical Genomics Research Department, King Abdullah International Medical Research Center (KAIMRC), King Saud bin Abdulaziz University for Health Science, Ministry of National Guard-Health Affairs (MNGHA), Riyadh, Saudi Arabia.
King Abdulaziz University · SAImam Abdulrahman Bin Faisal University · SAKing Abdullah International Medical Research Center · SAUniversity of Swabi · PKNational Guard Health Affairs · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GLI1novel missense variantPAPA8post-axial polydactyly type Awhole exome sequencing

Identifiers

PMID34721536
PMCPMC8554680
OpenAlexW3206564615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.