ArticleFrontiers in genetics2021
Evaluating Causal Relationship Between Metabolites and Six Cardiovascular Diseases Based on GWAS Summary Statistics.
Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Causal relationship between blood metabolites and risk of five infections: a Mendelian randomization study.BMC infectious diseases · 2023Pooled it
- Multi-omic definition of metabolic obesity through adipose tissue-microbiome interactions.Nature medicine · 2026Article
- Multiomics insight into the role of glucagon-like peptide-1 receptor agonists in heart failure.ESC heart failure · 2025Article
- Watercress (Life (Basel, Switzerland) · 2025Review
- Association Between Serum Apolipoprotein B and Bone Mineral Density and the Effects of Cardiovascular Disease Mediation: Results From the NHANES 2011-2016 and a Mendelian Randomization Study.Reviews in cardiovascular medicine · 2025Article
- Elevated isoleucine may be a protective factor for primary hypertension: A pooled causal effect study.Medicine · 2025Article
- Causality of metabolites and metabolic pathways on cholestatic liver diseases: a Mendelian randomization study.Frontiers in medicine · 2024Article
- Causal association between blood metabolites and risk of hypertension: a Mendelian randomization study.Frontiers in cardiovascular medicine · 2024Article
- Association between human blood metabolome and the risk of hypertension.BMC genomic data · 2023Article
- Systematic metabolomic studies identified adult adiposity biomarkers with acetylglycine associated with fat lossFrontiers in molecular biosciences · 2023Article
- Identification of blood metabolites linked to the risk of cholelithiasis: a comprehensive Mendelian randomization study.Hepatology international · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular diseases (CVDs) remain the main cause of morbidity and mortality worldwide. The pathological mechanism and underlying biological processes of these diseases with metabolites remain unclear. In this study
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.