ArticleDementia and geriatric cognitive disorders extra
Determinants of Caregiver Burden in Early-Onset Dementia.
Article in Dementia and geriatric cognitive disorders extra. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Environmental and lifestyle risk factors for early-onset dementia: a systematic review.Acta bio-medica : Atenei Parmensis · 2022Pooled it
- Quantification of Phosphorylated Tau Protein in Alzheimer's Disease Patients' Fluids With Electrolyte-Gated Organic Transistor Biosensors.Advanced healthcare materials · 2026Article
- Outdoor light at night and neuropsychiatric symptoms in dementia.GeroScience · 2026Article
- Longitudinal investigation of psychological adaptation and its determinants in primary caregivers following thyroid cancer surgery.Frontiers in medicine · 2026Article
- Pain in people with dementia is a significant contributor to increased professional caregiver burden: results of an observation study.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
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- Psychosis in Neurocognitive Disorder Among Ethnoculturally Diverse Older Persons.Neurology. Clinical practice · 2025Article
- Designing an intervention to improve cognitive evaluations in primary care.Implementation science communications · 2025Article
- Applying recommendations for diagnostic disclosure of mild cognitive impairment and dementia: Practical guidance for clinicians.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Observational
- Contributors to caregiver burden, depression, and anxiety in the partners of professional American-style football players: a cross-sectional study.Frontiers in psychology · 2025Article
- Atrial Fibrillation and Other Cardiovascular Factors and the Risk of Dementia: An Italian Case-Control Study.International journal of environmental research and public health · 2024Article
- Partners' experiences of their loved ones' trauma and PTSD: An ongoing journey of loss and gain.PloS one · 2024Article
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- Area-Level Infant Mortality Exposure in Early Life and Alzheimer's Disease Mortality: Examining Variation Based on Age, Sex, and Place of Birth.Journal of Alzheimer's disease : JAD · 2023Article
- Role of caregivers on medication adherence management in polymedicated patients with Alzheimer's disease or other types of dementia.Frontiers in public health · 2022Observational
- Global, regional, and national burdens of early-onset Alzheimer's disease and other dementias in women, 1990 to 2021.Journal of Alzheimer's disease reportsArticle
- The Burden and Coping Mechanisms among the Caregivers of Immobilized Elderly Patients: A Multinational Comparative Study.Iranian journal of nursing and midwifery researchArticle
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCaregivers of patients with early-onset dementia (EOD) experience high levels of burden, which is known to be affected by caregivers' psychological features as well as by patients' and caregivers' demographical and social variables. Although potential clinical, demographical, and social determinants have been separately examined, it is not known how they reciprocally interact.
methodsNinety-two consecutive patient-caregiver dyads were recruited from the Cognitive Neurology Clinics of Modena, Northern Italy. Caregivers were asked to fill in questionnaires regarding their burden, psychological distress, and family economic status. Data were analyzed with multivariable regression models and then entered in a mediation model.
resultsCaregiver burden was positively related to female caregiver sex, spousal relationship to the patient, severity of patient's behavioral symptoms, diagnostic delay, and financial distress of the family. It was negatively related to disease duration, patient's education, region of birth, caregiver age, number of caregiver's days off work, number of offspring, and caregiver perception of patient's quality of life. While the effect of caregiver age, diagnostic delay, and of proxies of family or social network directly impacted on caregiver's burden, the effect of patient's disease duration, being a wife caregiver, financial distress, and number of caregiver's days off work was entirely mediated by the level of caregiver psychological distress.
conclusionsBoth direct actions (such as increasing social networks and shortening diagnostic delay) and indirect actions aimed at reducing psychological distress (such as increasing the number of caregiver's days off work and financial support) should be planned to reduce caregiver's burden.
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