Evidence map›Paper›PMID 34721415›Full record

ArticleFrontiers in immunology2021

Endogenous α7 nAChR Agonist SLURP1 Facilitates

Xiaolong He, Lei Wang, Liqun Liu, Jie Gao, Beiguo Long, Feng Chi, Tongtong Hu, Yu Wan, Zelong Gong, Li Li and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Xiaolong HeDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Lei WangDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Liqun LiuSaban Research Institute, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Jie GaoDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Beiguo LongDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Feng ChiSaban Research Institute, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Tongtong HuDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Yu WanDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Zelong GongDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Li LiSaban Research Institute, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, United States.
Peilin ZhenDepartment of Infectious Disease, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China.
Tiesong ZhangKunming Key Laboratory of Children Infection and Immunity, Yunnan Institute of Pediatrics, Kunming Children's Hospital, Kunming, China.
Hong CaoDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Sheng-He HuangDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Southern Medical University · CNKunming Children's Hospital · CNJiangmen Central Hospital · CNCentral South University · CNChildren's Hospital of Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha 7 nicotinic acetylcholine receptor (α7 nAChR) is critical for the pathogenesis of

Indexed as

Blood-Brain Barrieralpha7 Nicotinic Acetylcholine ReceptorAnimalsAntigens, LyCell LineCerebrospinal FluidEndothelial CellsEscherichia coliEscherichia coli InfectionsHippocampusHost-Pathogen InteractionsHumansInfant, NewbornMemantineMeningitis, Escherichia coliMicealpha7 Nicotinic Acetylcholine ReceptorAntigens, LyChrna7 protein, mouseMemantineRecombinant ProteinsSLURP1 protein, humanSLURP-1 protein, mouseUrokinase-Type Plasminogen Activatorblood-brain barrierE. coli K1 meningitisinflammationSLURP1α7 nAChR

Identifiers

PMID34721415
PMCPMC8552013
OpenAlexW3206265027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.