Evidence map›Paper›PMID 34721406›Full record

ArticleFrontiers in immunology2021

Convenient Auto-Processing Vector Based on Bamboo Mosaic Virus for Presentation of Antigens Through Enzymatic Coupling.

Ming-Hao Yang, Chung-Chi Hu, Chi-Hzeng Wong, Jian-Jong Liang, Hui-Ying Ko, Meng-Hsun He, Yi-Ling Lin, Na-Sheng Lin, Yau-Heiu Hsu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ming-Hao YangGraduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Chung-Chi HuGraduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Chi-Hzeng WongGraduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Jian-Jong LiangInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Hui-Ying KoInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Meng-Hsun HeInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Yi-Ling LinInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Na-Sheng LinInstitute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Yau-Heiu HsuGraduate Institute of Biotechnology, National Chung Hsing University, Taichung, Taiwan.
National Chung Hsing University · TWInstitute of Biomedical Sciences, Academia Sinica · TWInstitute of Plant and Microbial Biology, Academia Sinica · TWAcademia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a new binary epitope-presenting CVP platform based on bamboo mosaic virus (BaMV) by using the sortase A (SrtA)-mediated ligation technology. The reconstructed BaMV genome harbors two modifications: 1) a coat protein (CP) with N-terminal extension of the tobacco etch virus (TEV) protease recognition site plus 4 extra glycine (G) residues as the SrtA acceptor; and 2) a TEV protease coding region replacing that of the triple-gene-block proteins. Inoculation of such construct, pKB5G, on

Indexed as

AminoacyltransferasesAnimalsAntibodies, NeutralizingAntigens, ViralBacterial ProteinsCell LineCysteine EndopeptidasesDisease Models, AnimalEncephalitis, JapaneseEncephalitis Virus, JapaneseEndopeptidasesEscherichia coliFemaleGenetic VectorsImmunogenicity, VaccineJapanese Encephalitis VaccinesAminoacyltransferasesAntibodies, NeutralizingAntigens, ViralBacterial ProteinsCysteine EndopeptidasesEndopeptidasesJapanese Encephalitis Vaccinessortase ATEV proteaseantigen presentation platformBamboo mosaic virus (BaMV)chimeric virus particle (CVP)Japanese encephalitis virus (JEV)nanoparticlesortase ATobacco etch virus protease (TEVp)virus-like particle (VLP)

Identifiers

PMID34721406
PMCPMC8551676
OpenAlexW3205139576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.