Evidence map›Paper›PMID 34721290›Full record

ArticleFrontiers in endocrinology2021

Retrospective Analysis of Fondaparinux and Low-Molecular-Weight Heparin in the Treatment of Women With Recurrent Spontaneous Abortion.

Long Zhao, Shuqin Bi, Jinhua Fu, Lijuan Qi, Lin Li, Yinghui Fu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Long ZhaoDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Shuqin BiDepartment of Obstetrics, Qingdao Jinhua Gynecology Hospital, Qingdao, China.
Jinhua FuDepartment of Obstetrics, Qingdao Jinhua Gynecology Hospital, Qingdao, China.
Lijuan QiDepartment of Obstetrics, Qingdao Jinhua Gynecology Hospital, Qingdao, China.
Lin LiDepartment of Nephrology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yinghui FuDepartment of Obstetrics, Qingdao Jinhua Gynecology Hospital, Qingdao, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To compare the clinical efficacy of fondaparinux and LMWH and provide clinical evidence for the effectiveness of fondaparinux in the treatment of recurrent spontaneous abortion caused by PTS. Methods: A retrospective analysis was conducted for 120 patients diagnosed with a recurrent spontaneous abortion caused by PTS in Qingdao Jinhua Women's Hospital from March 2019 to April 2020. The patients were divided into two groups: 68 cases in the control group, treated with LMWH, 52 cases in the observational group, treated with fondaparinux. The pregnancy outcomes and adverse reactions between the two groups of recurrent miscarriage patients were compared. Results: No significant difference was detected in the general data between the two groups of patients before treatment (P>0.05). In the observational group, the R value was increased, and the α and MA values were decreased after three months of treatment compared to those before treatment (P Conclusions: In this study, no significant difference was detected in the pregnancy outcome between fondaparinux and LMWH in the treatment of recurrent spontaneous abortion caused by PTS, but fondaparinux had a low occurrence rate of adverse reactions and high safety.

Indexed as

Abortion, HabitualAdultCase-Control StudiesFactor Xa InhibitorsFemaleFibrinolytic AgentsFollow-Up StudiesFondaparinuxHeparin, Low-Molecular-WeightHumansPregnancyPrognosisRetrospective StudiesFactor Xa InhibitorsFibrinolytic AgentsFondaparinuxHeparin, Low-Molecular-Weightanticoagulationfondaparinuxlow-molecular-weight heparinrecurrent spontaneous abortionthrombelastography

Identifiers

PMID34721290
PMCPMC8553245
OpenAlexW3205886902

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.