Evidence map›Paper›PMID 34721066›Full record

ArticleFrontiers in physiology2021

Mitochondrial Contributions in the Genesis of Delayed Afterdepolarizations in Ventricular Myocytes.

Vikas Pandey, Lai-Hua Xie, Zhilin Qu, Zhen Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Vikas PandeyDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Lai-Hua XieDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, NJ, United States.
Zhilin QuDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Zhen SongDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
University of California, Los Angeles · USPeng Cheng Laboratory · CNRutgers, The State University of New Jersey · US

Funding

SK Current, beta-3 adrenoceptor activation and Sex Differences in Ventricular ArrhythmogenesisR01HL139829 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI PENG-SHENG CHEN, ZHILIN QU · 2018 to 2026
$4.5M
Mitochondria and arrhythmogenic calicum cycling dynamics in the heartR01HL133294 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI QU, ZHILIN, XIE, LAI-HUA · 2017 to 2020
$2.8M
Ferroptosis in the Heart: Iron Calcium Crosstalk and CompartmentalizationR01HL157116 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI GWATHMEY, JUDITH K, XIE, LAI-HUA · 2022 to 2025
$2.4M
A population-based in silico platform for arrhythmia predictionR01HL134709 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI QU, ZHILIN · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL133294NHLBI NIH HHS R01 HL134709NHLBI NIH HHS R01 HL139829NHLBI NIH HHS R01 HL157116
6 · The paper itself

Abstract

Mitochondria fulfill the cell's energy demand and affect the intracellular calcium (Ca

Indexed as

Ca2+ signalingCa2+ wavecardiac celldelayed afterdepolarizationmitochondrion

Identifiers

PMID34721066
PMCPMC8551757
OpenAlexW3206995125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.