ArticleFrontiers in pharmacology2021
The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations.
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Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
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Who cites it
20 citing papers in PubMed.
- Pharmacogenetics of Mycophenolic Acid in Patients of African Descent: Underrepresentation of African Data.Clinical and translational science · 2026Review
- Strengthening Pharmacogenomics Implementation in Africa: Challenges and Opportunities - A Narrative Review.Health science reports · 2026Article
- Article
- A call to action for pharmacogenomics stewardship in South Africa.Frontiers in pharmacology · 2026Article
- Artificial intelligence coupled to pharmacometrics modelling to tailor malaria and tuberculosis treatment in Africa.Nature communications · 2025Article
- Characterization of the complex TB pharmacogenomic landscape in Africa using bioinformatic tools.Briefings in bioinformatics · 2025Article
- Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations.Molecular genetics and genomics : MGG · 2024Article
- The Case for Pre-Emptive Pharmacogenetic Screening in South Africa.Journal of personalized medicine · 2024Article
- Characterization ofPharmacogenomics · 2023Article
- Pharmacogenetics as part of recommended precision medicine for tuberculosis treatment in African populations: Could it be a reality?Clinical and translational science · 2023Review
- Pharmacogenetics of 6-mercaptopurine in a black Zimbabwean cohort treated for acute lymphoblastic leukaemia.Pharmacogenomics · 2023Article
- Characterization of CYP2D6 Pharmacogenetic Variation in Sub-Saharan African Populations.Clinical pharmacology and therapeutics · 2023Article
- Characterization of NovelJournal of personalized medicine · 2022Article
- Clinical trial diversity: An opportunity for improved insight into the determinants of variability in drug response.British journal of clinical pharmacology · 2022Review
- African Genomic Medicine Portal: A Web Portal for Biomedical Applications.Journal of personalized medicine · 2022Article
- SWAAT Bioinformatics Workflow for Protein Structure-Based Annotation of ADME Gene Variants.Journal of personalized medicine · 2022Article
- Pharmacogenomics at the post-pandemic: If not now, then when?Frontiers in pharmacology · 2022Article
- Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing.Frontiers in pharmacology · 2022Article
- Hepatic Models in Precision Medicine: An African Perspective on Pharmacovigilance.Frontiers in genetics · 2022Article
- Single Nucleotide Polymorphism Induces Divergent Dynamic Patterns in CYP3A5: A Microsecond Scale Biomolecular Simulation of Variants Identified in Sub-Saharan African Populations.International journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
25 authors.
Jorge E B da RochaSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Houcemeddine OthmanSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Gerrit BothaComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
Laura CottinoSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
David TwesigomweSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Samah AhmedCentre for Bioinformatics and Systems Biology, Faculty of Science, University of Khartoum, Khartoum, Sudan.
Britt I DrögemöllerDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB, Canada.
Faisal M FadlelmolaCentre for Bioinformatics and Systems Biology, Faculty of Science, University of Khartoum, Khartoum, Sudan.
Philip MachanickDepartment of Computer Science, Rhodes University, Makhanda, South Africa.
Mamana MbiyavangaComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
Sumir PanjiComputational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa.
Galen E B WrightNeuroscience Research Program, Winnipeg Health Sciences Centre and Max Rady College of Medicine, Kleysen for Advanced Medicine, University of Manitoba, Winnipeg, MB, Canada.
Clement AdebamowoInstitute for Human Virology, Abuja, Nigeria.
Mogomotsi MatshabaBotswana-Baylor Children's Clinical Center of Excellence, Gaborone, Botswana.
Michéle RamsaySydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Gustave SimoMolecular Parasitology and Entomology Unit, Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon.
Martin C SimuunzaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Caroline T TiemessenCentre for HIV and STIs, National Institute for Communicable Diseases, National Health Laboratory Services and Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Sandra BaldwinDrug Metabolism and Pharmacokinetics, GlaxoSmithKline R&D, Ware, United Kingdom.
Mathias ChianoHuman Genetics, GlaxoSmithKline R&D, Stevenage, United Kingdom.
Charles CoxHuman Genetics, GlaxoSmithKline R&D, Stevenage, United Kingdom.
Annette S GrossClinical Pharmacology Modelling and Simulation, GlaxoSmithKline R&D, Sydney, NSW, Australia.
Pamela ThomasData and Computational Sciences, GlaxoSmithKline R&D, Stevenage, United Kingdom.
Francisco-Javier GamoGlobal Health, GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain.
Scott HazelhurstSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Funding
H3ABioNet: a sustainable African Bioinformatics Network for H3AfricaU41HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2012 to 2017
$14.8MNHGRI NIH HHS U41 HG006941
Abstract
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Indexed as
ADMEAfricaCNVgenetic diversitypharmacogenomics
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.