Evidence map›Paper›PMID 34720995›Full record

ArticleFrontiers in aging neuroscience2021

High Blood Uric Acid Is Associated With Reduced Risks of Mild Cognitive Impairment Among Older Adults in China: A 9-Year Prospective Cohort Study.

Chen Chen, Xueqin Li, Yuebin Lv, Zhaoxue Yin, Feng Zhao, Yingchun Liu, Chengcheng Li, Saisai Ji, Jinhui Zhou, Yuan Wei and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Association between higher serum uric acid levels and cognitive function: a systematic review and meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Serum uric acid levels and longitudinal change in cognitive function in older adults: a sex-stratified population-based study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
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  10. Review
  11. Review
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  15. Article
  16. The Role of Uric Acid in Human Health: Insights from theJournal of personalized medicine · 2023
    Review
  17. Observational
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Chen ChenChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Xueqin LiDepartment of Big Data in Health Science, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.
Yuebin LvChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhaoxue YinDivision of Non-communicable Disease and Healthy Ageing Management, Chinese Center for Disease Control and Prevention, Beijing, China.
Feng ZhaoChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Yingchun LiuChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Chengcheng LiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Saisai JiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Jinhui ZhouChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Yuan WeiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Xingqi CaoDepartment of Big Data in Health Science, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.
Jiaonan WangChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Heng GuChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Feng LuBeijing Municipal Health Commission Information Center, Beijing Municipal Health Commission Policy Research Center, Beijing, China.
Zuyun LiuDepartment of Big Data in Health Science, School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.
Xiaoming ShiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Chinese Center For Disease Control and Prevention · CNNanjing Medical University · CNZhejiang University · CNBeijing Municipal Education Commission · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cognitive functionmild cognitive impairmentolder adultsprospective cohort studyuric acid

Identifiers

PMID34720995
PMCPMC8552040
OpenAlexW3207224983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.