Evidence map›Paper›PMID 34720789›Full record

ReviewMicrofluidics and nanofluidics2021

Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives.

Prapti Pattanayak, Sachin Kumar Singh, Monica Gulati, Sukriti Vishwas, Bhupinder Kapoor, Dinesh Kumar Chellappan, Krishnan Anand, Gaurav Gupta, Niraj Kumar Jha, Piyush Kumar Gupta and 5 more

Abstract readReview
In one paragraph

Review in Microfluidics and nanofluidics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed.

  1. Review
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  14. Development ofBeilstein journal of nanotechnology · 2026
    Article
  15. Article
  16. Review
  17. Lanthanide Nanotheranostics in Radiotherapy.International journal of molecular sciences · 2025
    Review
  18. Review
  19. Review
  20. Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Prapti PattanayakSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411 India.
Sachin Kumar SinghSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411 India.ORCID 0000-0003-3823-6572
Monica GulatiSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411 India.
Sukriti VishwasSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411 India.
Bhupinder KapoorSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411 India.
Dinesh Kumar ChellappanSchool of Pharmacy, International Medical University, Bukit Jalil, 57000 Kuala Lumpur, Malaysia.
Krishnan AnandDepartment of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa.
Gaurav GuptaSchool of Pharmacy, Suresh Gyan Vihar University, Mahal Road, Jagatpura, Jaipur, India.
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Greater Noida, Uttar Pradesh 201310 India.
Piyush Kumar GuptaDepartment of Life Sciences, School of Basic Sciences and Research, Sharda University, Plot no. 32-34, Knowledge Park III, Greater Noida, Uttar Pradesh 201310 India.
Parteek PrasherDepartment of Chemistry, University of Petroleum & Energy Studies, Energy Acres, Dehradun, 248007 India.
Kamal DuaFaculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007 Australia.
Harish DurejaDepartment of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana 12401 India.
Deepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, 173229 India.
Vijay KumarSchool of Bioengineering and Bioscience, Lovely Professional University, Phagwara, Punjab 144411 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidic chip technology is an emerging tool in the field of biomedical application. Microfluidic chip includes a set of groves or microchannels that are engraved on different materials (glass, silicon, or polymers such as polydimethylsiloxane or PDMS, polymethylmethacrylate or PMMA). The microchannels forming the microfluidic chip are interconnected with each other for desired results. This organization of microchannels trapped into the microfluidic chip is associated with the outside by inputs and outputs penetrating through the chip, as an interface between the macro- and miniature world. With the help of a pump and a chip, microfluidic chip helps to determine the behavioral change of the microfluids. Inside the chip, there are microfluidic channels that permit the processing of the fluid, for example, blending and physicochemical responses. Microfluidic chip has numerous points of interest including lesser time and reagent utilization and alongside this, it can execute numerous activities simultaneously. The miniatured size of the chip fastens the reaction as the surface area increases. It is utilized in different biomedical applications such as food safety sensing, peptide analysis, tissue engineering, medical diagnosis, DNA purification, PCR activity, pregnancy, and glucose estimation. In the present study, the design of various microfluidic chips has been discussed along with their biomedical applications.

Indexed as

Biomedical applicationMicrofluidic chipMicrofluidic technologyMicrominiaturization

Identifiers

PMID34720789
PMCPMC8547131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.