Evidence map›Paper›PMID 34720552›Full record

ArticleEthnicity & disease2021

Central Blood Pressure and Subclinical Atherosclerotic Risk in Young Hispanic American Women.

Patricia Pagan Lassalle, Jacob P DeBlois, Allie Keller, Lee Stoner, Kevin S Heffernan

Open access · bronzeAbstract read
In one paragraph

Article in Ethnicity & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patricia Pagan LassalleSyracuse University, Exercise Science, Syracuse NY.
Jacob P DeBloisSyracuse University, Exercise Science, Syracuse NY.
Allie KellerSyracuse University, Exercise Science, Syracuse NY.
Lee StonerUniversity of North Carolina, Department of Exercise and Sport Science, Chapel Hill, NC.
Kevin S HeffernanSyracuse University, Exercise Science, Syracuse NY.
Syracuse University · USUniversity of North Carolina at Chapel Hill · US

Funding

Racial Differences in Arterial Stiffness and Cognitive Function.R03MD011306 · NIMHD · SYRACUSE UNIVERSITY · PI HEFFERNAN, KEVIN SCOTT · 2017 to 2018
$150k
NIMHD NIH HHS R03 MD011306
6 · The paper itself

Abstract

backgroundThe incidence of younger women being hospitalized from cardiovascular disease (CVD) events is on the rise. Hispanic women are generally thought to have higher CVD risk factor burden than non-Hispanic White (NHW) women yet Hispanic Americans have lower mortality from CVD. Traditional measures of CVD may not accurately capture CVD risk in Hispanic Americans. Hence, the purpose of this study was to assess the impact of ethnicity on vascular reactivity and central hemodynamic load to gain insight into subclinical CVD risk in young women.

methodsBrachial flow-mediated dilation (FMD), low-flow mediated constriction (L-FMC), carotid-femoral pulse wave velocity (cfPWV), and pulse wave analysis (from synthesized aortic pressure waveforms) were measured in 25 Hispanic women and 31 NHW women aged between 18-35 years. FMD and L-FMC were combined to provide an index of total vessel reactivity.

resultsNHW and Hispanic women did not differ in age or traditional CVD risk factors (P>.05 for all). Compared with NHW women, Hispanic women had greater vascular reactivity (8.7±4.1 vs 11.7±4.1 %, P=.011), lower central pulse pressure (28±5 vs 24±3 mm Hg, P=.001) and lower pressure from wave reflections (12±2 vs 10±1 mm Hg, P=.001). There were no differences in cfPWV between NHW women and Hispanic women (5.4±0.7 vs 5.3±0.7 m/s, P=.73).

conclusionYoung Hispanic women have greater vascular reactivity and lower central pulsatile hemodynamic load compared with NHW women, suggesting lower subclinical CVD risk.

Indexed as

Cardiovascular DiseasesVascular StiffnessAdolescentAdultBlood PressureBrachial ArteryFemaleHispanic or LatinoHumansPulse Wave AnalysisRisk FactorsYoung AdultArterial StiffnessBlood PressureCardiovascular DiseaseEthnicity

Identifiers

PMID34720552
PMCPMC8545478
OpenAlexW3208240367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.