ArticleJournal of photochemistry and photobiology. A, Chemistry2022
Evaluating the Merit of a Syringol Derived Fluorophore as a Charge Transfer Probe for Detection of Serum Albumins.
Article in Journal of photochemistry and photobiology. A, Chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- A NIR-Fluorochrome for Live Cell Dual Emission and Lifetime Tracking from the First Plasma Membrane Interaction to Subcellular and Extracellular Locales.Molecules (Basel, Switzerland) · 2024Article
- In situ generation of a Zwitterionic fluorescent probe for detection of human serum albumin protein.Analytical biochemistry · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
In this article a syringol-π-benz[e]indolium based donor-acceptor fluorophore has been reported. The fluorophore shows a solvent polarity dependent change in the absorption and emission spectra in solution. A combined spectroscopic and time dependent density functional theory (TDDFT) studies reveal higher dipole moment of the fluorophore in the excited state, resulting positive solvatochromism. In physiological pH, the phenol group in the fluorophore is easily deprotonated owing to the electron pulling effect of the substituents. Consequently, the phenolate (PhO-) becomes a strong active donor in the new donor-acceptor pair. In aqueous solution, the new phenolate fluorochrome shows negligible fluorescence due to energy loss via non-radiative pathways from the low-lying polar excited states. The fluorochrome can detect human and bovine serum albumins in physiological buffer solution with high selectivity. The underlying mechanism of human serum albumin (HSA) detection was estimated to be strong (1.46 × 10
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