Evidence map›Paper›PMID 34720528›Full record

ReviewWorld journal of gastroenterology2021

Intraoperative use of indocyanine green fluorescence imaging in rectal cancer surgery: The state of the art.

Roberto Peltrini, Mauro Podda, Simone Castiglioni, Maria Michela Di Nuzzo, Michele D'Ambra, Ruggero Lionetti, Maurizio Sodo, Gaetano Luglio, Felice Mucilli, Salomone Di Saverio and 2 more

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  13. Advances in beyond total mesorectal excision surgery: Behind the scenes.World journal of gastrointestinal surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Roberto PeltriniDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy. roberto.peltrini@gmail.com.
Mauro PoddaDepartment of Emergency Surgery, Cagliari University Hospital "Duilio Casula", Azienda Ospedaliero-Universitaria di Cagliari, Cagliari 09100, Italy.
Simone CastiglioniDepartment of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio Chieti-Pescara, Pescara 65100, Italy.
Maria Michela Di NuzzoDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Michele D'AmbraDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Ruggero LionettiDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Maurizio SodoDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Gaetano LuglioDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Felice MucilliDepartment of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio Chieti-Pescara, Pescara 65100, Italy.
Salomone Di SaverioDepartment of General Surgery, University of Insubria, ASST Sette Laghi, Varese 21100, Italy.
Umberto BracaleDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Francesco CorcioneDepartment of Public Health, University of Naples Federico II, Napoli 80131, Italy.
Azienda Ospedaliero-Universitaria Cagliari · ITUniversity of Chieti-Pescara · ITUniversity of Insubria · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indocyanine green (ICG) fluorescence imaging is widely used in abdominal surgery. The implementation of minimally invasive rectal surgery using new methods like robotics or a transanal approach required improvement of optical systems. In that setting, ICG fluorescence optimizes intraoperative vision of anatomical structures by improving blood and lymphatic flow. The purpose of this review was to summarize all potential applications of this upcoming technology in rectal cancer surgery. Each type of use has been separately addressed and the evidence was investigated. During rectal resection, ICG fluorescence angiography is mainly used to evaluate the perfusion of the colonic stump in order to reduce the risk of anastomotic leaks. In addition, ICG fluorescence imaging allows easy visualization of organs such as the ureter or urethra to protect them from injury. This intraoperative technology is a valuable tool for conducting lymph node dissection along the iliac lymphatic chain or to better identifying the rectal dissection planes when a transanal approach is performed. This is an overview of the applications of ICG fluorescence imaging in current surgical practice and a synthesis of the results obtained from the literature. Although further studies are need to investigate the real clinical benefits, these findings may enhance use of ICG fluorescence in current clinical practice and stimulate future research on new applications.

Indexed as

Indocyanine GreenRectal NeoplasmsAnastomotic LeakHumansOptical ImagingRectumIndocyanine GreenAnastomotic leakageFluorescence imagingIndocyanine greenNear infraredRectal cancerTotal mesorectal excision

Identifiers

PMID34720528
PMCPMC8517789
OpenAlexW3207660977

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.