Evidence map›Paper›PMID 34720339›Full record

ArticleJournal of magnetism and magnetic materials2022

Highly aminated iron oxide nanoworms for simultaneous manufacturing and labeling of chimeric antigen receptor T cells.

Wei Zhang, Hanmant Gaikwad, Ernest V Groman, Enkhtsetseg Purev, Dmitri Simberg, Guankui Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of magnetism and magnetic materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Advances in nano-immunotherapy for hematological malignancies.Experimental hematology & oncology · 2024
    Review
  2. Nanodrugs Targeting T Cells in Tumor Therapy.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wei ZhangDivision of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Hanmant GaikwadTranslational Bio-Nanosciences Laboratory, School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Ernest V GromanTranslational Bio-Nanosciences Laboratory, School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Enkhtsetseg PurevDivision of Hematology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Dmitri SimbergTranslational Bio-Nanosciences Laboratory, School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
Guankui WangTranslational Bio-Nanosciences Laboratory, School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
University of Colorado Anschutz Medical Campus · US

Funding

The Alternative Complement Pathway and Hemocompatibility of NanosurfacesR01AI154959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Dmitri Simberg · 2020 to 2026
$3.5M
Painted erythrocyte carriers for therapy of acute myeloid leukemiaR01CA194058 · NCI · UNIVERSITY OF COLORADO DENVER · PI SIMBERG, DMITRI · 2016 to 2020
$1.8M
The alternative complement pathway and hemocompatibility of nanosurfacesR01EB022040 · NIBIB · UNIVERSITY OF COLORADO DENVER · PI SIMBERG, DMITRI · 2016 to 2019
$1.4M
NCI NIH HHS R01 CA194058NIAID NIH HHS R01 AI154959NIBIB NIH HHS R01 EB022040
6 · The paper itself

Abstract

Cell based therapies including chimeric antigen receptor (CAR) T cells are promising for treating leukemias and solid cancers. At the same time, there is interest in enhancing the functionality of these cells

Indexed as

CAR-Tcell traffickingiron oxideleukemiamagnetic labelingnanoworm

Identifiers

PMID34720339
PMCPMC8553019
OpenAlexW3197612963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.