ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.
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In one paragraph
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Targeting ion channel dysregulation in tumors: emerging therapeutic opportunities.Trends in pharmacological sciences · 2026Review
- Extracellular matrix stiffness conditions glioblastoma cells for long-term migration: Mechanical memory as a driver of invasion and recurrence in glioblastoma.Neuro-oncology · 2026Review
- HAS1Journal of experimental & clinical cancer research : CR · 2025Article
- Spatially Resolved Tumor Ecosystems and Cell States in Gastric Adenocarcinoma Progression and Evolution.Cancer discovery · 2025Article
- Malignant Cells Beyond the Tumor Core: The Non-Negligible Factor to Overcome the Refractory of Glioblastoma.CNS neuroscience & therapeutics · 2025Review
- CD57 defines a novel cancer stem cell that drive invasion of diffuse pediatric-type high grade gliomas.British journal of cancer · 2024Article
- Article
- Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.Cancers · 2024Review
- KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11.Cancer cell international · 2024Article
- Article
- Silencing GMPPB Inhibits the Proliferation and Invasion of GBM via Hippo/MMP3 Pathways.International journal of molecular sciences · 2023Article
- Tumor microenvironment in a minipig model of spinal cord glioma.Journal of translational medicine · 2023Article
- Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models.Journal of translational medicine · 2023Article
- A diagnostic circulating miRNA signature as orchestrator of cell invasion via TKS4/TKS5/EFHD2 modulation in human gliomas.Journal of experimental & clinical cancer research : CR · 2023Article
- Aquaporins and Ion Channels as Dual Targets in the Design of Novel Glioblastoma Therapeutics to Limit Invasiveness.Cancers · 2023Review
- Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 6 institutions in 4 countries.
Yulun HuangDepartment of Neurosurgery, Dushu Lake Hospital, Soochow University, Suzhou, 205124, China.
Lin QiTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Mari KogisoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Yuchen DuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Frank K BraunTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Huiyuan ZhangTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
L Frank HuangDepartment of Systems Medicine and Bioegineering, Houston Methodist Hospital Research Institute and Cancer Center, Weill Cornell Medicine, Houston, TX, 77030, USA.
Sophie XiaoProgram of Precision Medicine PDOX Modeling of Pediatric Tumors, Ann & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Wan-Yee TeoHumphrey Oei Institute of Cancer Research, National Cancer Center Singapore, Singapore, 169610, Singapore.
Holly LindsayTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Sibo ZhaoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Patricia BaxterTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Jack M F SuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Adekunle AdesinaDepartment of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Jianhua YangTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Sebastian BrabetzHopp Children's Cancer Center (KiTZ), Heidelberg, 69120, Germany.
Marcel KoolHopp Children's Cancer Center (KiTZ), Heidelberg, 69120, Germany.
Stefan M PfisterHopp Children's Cancer Center (KiTZ), Heidelberg, 69120, Germany.
Murali ChintagumpalaTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Laszlo PerlakyTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Zhong WangDepartment of Neurosurgery and Brain and Nerve Research Laboratory, the First Affiliated Hospital, Soochow University, Suzhou, 215007, China.
Youxin ZhouDepartment of Neurosurgery and Brain and Nerve Research Laboratory, the First Affiliated Hospital, Soochow University, Suzhou, 215007, China.
Tsz-Kwong ManTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.
Xiao-Nan LiTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.ORCID 0000-0002-6719-3789
Baylor College of Medicine · USNorthwestern University · USGerman Cancer Research Center · DESoochow University · CNCincinnati Children's Hospital Medical Center · USNational University Cancer Institute, Singapore · SG
Funding
(PQD-5) Patient derived orthotopic xenograft models for drug response predictionR01CA185402 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LI, XIAONAN · 2014 to 2017
$1.3MCancer Prevention and Research Institute of Texas RP150032Department of Defense (DoD) W81XWH-20-1-0870Innovation & Pilot (RIP) Funding Awards from Cincinnati Children's Research FoundationNational Natural Science Foundation of China 8217112078National Science and Technology Resource Sharing Service Platform YCAYPT[2020]06-1NCI NIH HHS R01 CA185402NIH HHS CA185402St. Baldrick's Foundation 2532341503The CancerFree KIDS Foundation Fund and Research
Abstract
Diffuse invasion is the primary cause of treatment failure of glioblastoma (GBM). Previous studies on GBM invasion have long been forced to use the resected tumor mass cells. Here, a strategy to reliably isolate matching pairs of invasive (GBM
Indexed as
AnimalsBrain NeoplasmsCell Line, TumorCell ProliferationDisease Models, AnimalDissectionGlioblastomaHumansMiceMicroRNAsMicroRNAs4-aminopyridineglioblastomaKCNA1miRNApatient derived orthotopic xenograft
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.