ArticleProgress in orthodontics2021
Bionic effects of nano hydroxyapatite dentifrice on demineralised surface of enamel post orthodontic debonding: in-vivo split mouth study.
Article in Progress in orthodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Effect of COLasers in medical science · 2026Article
- Biomimetic Strategies for Subsurface Enamel Remineralization: Depth-Dependent Effects of Biomimetic Agents Compared with Fluoride.Biomimetics (Basel, Switzerland) · 2026Article
- Effect of the COFrontiers in dental medicine · 2026Article
- Effect of yttrium/lanthanum-doped ultrasonically assisted nano-hydroxyapatite on remineralization and bracket bond strength in artificial enamel lesions.BMC oral health · 2025Article
- Antimicrobial, remineralization, and infiltration: advanced strategies for interrupting dental caries.Medical review (2021) · 2025Review
- Comparative Evaluation of Three Remineralization Agents-Bioactive Glass, Nanohydroxyapatite and Casein Phosphopeptide-amorphous Calcium Phosphate Fluoride-based Slurry on Enamel Erosion of Primary Teeth: AnInternational journal of clinical pediatric dentistry · 2025Article
- The advancement of nanosystems for drug delivery in the prevention and treatment of dental caries.Frontiers in cellular and infection microbiology · 2025Review
- Comparing the remineralization potential of undemineralized dentin powder versus chicken eggshell powder on artificially induced initial enamel carious lesions: an in-vitro investigation.BMC oral health · 2024Article
- Article
- Nanohydroxyapatite in dentistry: A comprehensive review.The Saudi dental journal · 2023Article
- Improving Oral Health with Fluoride-Free Calcium-Phosphate-Based Biomimetic Toothpastes: An Update of the Clinical Evidence.Biomimetics (Basel, Switzerland) · 2023Review
- Remineralization of Artificially Demineralized Human Enamel and Dentin Samples by Zinc-Carbonate Hydroxyapatite Nanocrystals.Materials (Basel, Switzerland) · 2022Article
- Nano-Hydroxyapatite (nHAp) in the Remineralization of Early Dental Caries: A Scoping Review.International journal of environmental research and public health · 2022Article
- Hydroxyapatite synthesis and characterization from marine sources: A comparative study.Journal of oral biology and craniofacial researchArticle
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOrthodontic debonding procedure produces inevitable enamel surface alterations, sequelae to which are enamel demineralization, sensitivity and retention of pigments. Several agents have been employed to counterbalance the same. The purpose of this study was (1) To evaluate the hypothesis that no significant difference exists in the remineralising potential of nano hydroxyapatite (NanoHAP) dentifrice and fluoridated dentifrice after orthodontic debonding, (2) To estimate the enamel topographic parameters following use of nano HAP dentifrice, post orthodontic debonding.
methodsSixty upper first bi-cuspids (30 subjects) planned for therapeutic extraction for the orthodontic treatment were bonded with a light cured adhesive. Envelope method of randomisation was followed in this prospective in-vivo study. In each subject, one of the first premolar brackets was debonded using a debonding plier and polished following standard protocols. Envelope method of randomisation was used to determine the side of the premolar to be debonded first. Patient was advised to use fluoridated (Group I) dentifrice for the first 15 days, then the first premolar was covered with a heavy-bodied putty cap, extracted and subjected to atomic force microscopy (AFM). Contralateral first premolar was then debonded and polished using similar protocol, and patient was advised to use nano hydroxyapatite dentifrice (Group II) for next 15 days. The premolar was then extracted and analyzed for surface roughness using AFM. The remineralizing potential of dentifrices was assessed by evaluating surface roughness parameters of the two groups and were compared using a two-sample t test.
resultsA significant difference was found amongst Group I (Fluoridated dentifrice) and Group II (NanoHAP dentifrice) (p > 0.001***) for enamel surface roughness variables which reflect remineralising potential of dentifrices. Group II showed significantly lesser value of surface roughness characteristics.
conclusionsNanoHAP dentifrice was shown, after 15 days, to be superior to fluoridated dentifrice in remineralising enamel post orthodontic debonding.
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