Evidence map›Paper›PMID 34719417›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2021

Value of serum miR-922 and miR-506 expression levels in the diagnosis and prognostic assessment of childhood acute lymphoblastic leukemia.

Yi-Yue Zhu, Ri-Nuan Wu, Xia Li, Xiang-Bi Chen

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Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Diagnostic and prognostic significance of miR-486-5p in patients who underwent minimally invasive surgery for lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yi-Yue ZhuDepartment of Pediatrics, Sanya Maternal and Child Health Hospital, Sanya, Hainan 572000, China (Email: zhuyiyue2705@163.com).
Ri-Nuan Wu
Xia LiDepartment of Pediatrics, Sanya Maternal and Child Health Hospital, Sanya, Hainan 572000, China (Email: zhuyiyue2705@163.com).
Xiang-Bi ChenDepartment of Pediatrics, Sanya Maternal and Child Health Hospital, Sanya, Hainan 572000, China (Email: zhuyiyue2705@163.com).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the value of serum miR-922 and miR-506 expression levels in the diagnosis and prognostic assessment of childhood acute lymphoblastic leukemia (ALL).

methodsA total of 132 children with ALL (ALL group) and 80 healthy children (healthy control group) were prospectively selected in this study. Quantitative real-time polymerase chain reaction was used to measure the expression levels of serum miR-922 and miR-506 in both groups. Receiver operating characteristic (ROC) curves were plotted to analyze the diagnostic value of miR-922 and miR-506 for childhood ALL. The Kaplan-Meier method was used to plot survival curves, and multivariate COX regression models were used to analyze the risk factors for poor prognosis in children with ALL.

resultsThe ALL group had significantly higher expression levels of serum miR-922 and miR-506 than the control group (

conclusionsThe expression levels of miR-922 and miR-506 are of good value in the diagnosis and prognostic assessment of childhood ALL.

Indexed as

MicroRNAsPrecursor Cell Lymphoblastic Leukemia-LymphomaBiomarkers, TumorChildHumansKaplan-Meier EstimatePrognosisROC CurveBiomarkers, TumorMicroRNAsMIRN506 microRNA, humanMIRN922 microRNA, humanAcute lymphoblastic leukemiaChildDiagnostic valuemiR-506miR-922Prognosis

Identifiers

PMID34719417
PMCPMC8549642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.