ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022
Time trade-off with someone to live for: impact of having significant others on time trade-off valuations of hypothetical health states.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Preferences for health-related quality of life: do they vary by age? A systematic literature review on the EQ-5D measure.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Pooled it
- Time trade-off health state utility values for depression: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Pooled it
- Who Prefers Death to Life in Composite Time Trade-off Interviews, and Why? A Mixed-Methods Study among Asians in Singapore.The patient · 2026Article
- Article
- Estimating Health State Utilities for IDH-Mutant Diffuse Glioma.PharmacoEconomics - open · 2025Article
- Differences in health state valuation for small, low-risk thyroid cancer between general population and cancer survivors: a cross-sectional analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Health State Utilities Associated With Treatment Burden in Cystic Fibrosis: A Patient Valuation Study.CHEST pulmonary · 2025Article
- Assessment of health state utilities associated with adult and pediatric acid sphingomyelinase deficiency (ASMD).The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- What Makes the Time Tradeoff Tick? A Sociopsychological Explanation.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- Health utilities and willingness to pay in adult patients with coeliac disease in Hungary.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
backgroundThe TTO task involves giving up life years, i.e. living a shorter life, to avoid an undesirable health state. Despite being a hypothetical task, some respondents take other life factors into account when completing the task. This study explored the effect of having children and/or a partner on TTO valuations of hypothetical EQ-5D-5L health states in a valuation study of the general population.
methodsThe study used TTO data collected in a Norwegian EQ-5D-5L valuation study in 2019-2020, by one-to-one pc-assisted interviews following the EQ-VT protocol. We used regression modelling to determine the effect of significant others (having children or a partner) on disutility per health state from the TTO valuations.
results430 respondents were included [mean age 43.8 (SD 15.9) years, 58% female, 48% with children, 68% with a partner, 25% with neither children nor partner]. Having children and/or a partner was associated with lowered willingness to trade life years translating to higher elicited health state utilities (p < 0.01).
conclusionHaving significant others, or the lack of having significant others, was associated with respondents' valuation of hypothetical health states using TTO, more so than traditional sampling variables such as age and sex. Inadequate representativeness in terms of having significant others could bias health state preference values in valuation studies.
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