Evidence map›Paper›PMID 34718760›Full record

ArticleNucleic acids research2022

PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies.

Diego Fuentes, Manuel Molina, Uciel Chorostecki, Salvador Capella-Gutiérrez, Marina Marcet-Houben, Toni Gabaldón

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Pooled it
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  14. Linking phenotype to genotype using comprehensive genomic comparisons.Current opinion in genetics & development · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Diego FuentesBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.
Manuel MolinaBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.
Uciel ChorosteckiBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.ORCID 0000-0003-2229-6853
Salvador Capella-GutiérrezBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.ORCID 0000-0002-0309-604X
Marina Marcet-HoubenBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.
Toni GabaldónBarcelona Supercomputing Centre (BSC-CNS). Jordi Girona 29, 08034 Barcelona, Spain.ORCID 0000-0003-0019-1735
Barcelona Supercomputing Center · ESInstitució Catalana de Recerca i Estudis Avançats · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PhylomeDB is a unique knowledge base providing public access to minable and browsable catalogues of pre-computed genome-wide collections of annotated sequences, alignments and phylogenies (i.e. phylomes) of homologous genes, as well as to their corresponding phylogeny-based orthology and paralogy relationships. In addition, PhylomeDB trees and alignments can be downloaded for further processing to detect and date gene duplication events, infer past events of inter-species hybridization and horizontal gene transfer, as well as to uncover footprints of selection, introgression, gene conversion, or other relevant evolutionary processes in the genes and organisms of interest. Here, we describe the latest evolution of PhylomeDB (version 5). This new version includes a newly implemented web interface and several new functionalities such as optimized searching procedures, the possibility to create user-defined phylome collections, and a fully redesigned data structure. This release also represents a significant core data expansion, with the database providing access to 534 phylomes, comprising over 8 million trees, and homology relationships for genes in over 6000 species. This makes PhylomeDB the largest and most comprehensive public repository of gene phylogenies. PhylomeDB is available at http://www.phylomedb.org.

Indexed as

Databases, GeneticEvolution, MolecularSoftwareAnimalsGenomeHumansKnowledge BasesMolecular Sequence AnnotationPhylogenyPlantsProteomeProteome

Identifiers

PMID34718760
PMCPMC8728271
OpenAlexW3208467155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.