Evidence map›Paper›PMID 34718615›Full record

ArticleJournal of animal science2021

Genetic inbreeding depression load for fertility traits in Pura Raza Española mares.

Davinia I Perdomo-González, Antonio Molina, María J Sánchez-Guerrero, Ester Bartolomé, Luis Varona, Mercedes Valera

Open access · hybridAbstract read
In one paragraph

Article in Journal of animal science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Davinia I Perdomo-GonzálezDepartamento de Agronomía, ETSIA, Universidad de Sevilla, Sevilla, Spain.
Antonio MolinaDepartamento de Genética, Universidad de Córdoba, Córdoba, Spain.
María J Sánchez-GuerreroDepartamento de Biología Molecular e Ingeniería Bioquímica, Universidad Pablo de Olavide, Sevilla, Spain.
Ester BartoloméDepartamento de Agronomía, ETSIA, Universidad de Sevilla, Sevilla, Spain.
Luis VaronaDepartamento de Anatomía Embriología y Genética Animal, Instituto Agroalimentario de Aragón (IA2), Universidad de Zaragoza, Zaragoza, Spain.
Mercedes ValeraDepartamento de Agronomía, ETSIA, Universidad de Sevilla, Sevilla, Spain.
Universidad de Sevilla · ESUniversidad de Zaragoza · ESUniversidad Pablo de Olavide · ESUniversity of Córdoba · ES

Funding

Ministerio de Economía, Industria y Competitividad of the Spanish Government
6 · The paper itself

Abstract

Fertility is a key factor in the economic success of horse farms. However, it has received little attention due to the difficulty of measuring fertility objectively. Since its studbook creation (1912), the Pura Raza Española (PRE) breed has been a closed population and become high in-bred resulting in inbreeding depression (poor phenotypic values). Nevertheless, heterogeneous effects of inbreeding depression have been detected among founders and nonfounders. The aims of this study were (1) to analyze the genetic parameters for reproductive traits in mares of the PRE horse breed and (2) to estimate, for the first time, the inbreeding depression load associated with common ancestors of the breed. A total of 22,799 mares were analyzed. Heritability estimates ranged from 0.05 (interval between first and second foaling) to 0.16 (age at first foaling), whereas inbreeding depression load ratios ranged from 0.06 (parturition efficiency at 6th foaling) to 0.17 (age at first foaling), for a partial inbreeding coefficient of 10%. Although heritability is related to the variability expressed in the population, inbreeding depression load ratios measure the potential variability, whether expressed in the population or not. Most correlations between additive and inbreeding depression load genetic values were significant (P < 0.001) and of low to moderate magnitude. Our results confirm that individual inbreeding depression loads allow us to select horses that have a genetic value resistant to the deleterious effects of inbreeding.

Indexed as

Inbreeding DepressionAnimalsFemaleFertilityHorsesInbreedingPhenotypeReproductionfertilitygenetic parametershorsesinbreeding depressioninbreeding load heterogeneityreproductive efficiency

Identifiers

PMID34718615
PMCPMC8645228
OpenAlexW3208298559

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.