SynthesisInternational journal of epidemiology2022
Reduced mortality during the COVID-19 outbreak in Japan, 2020: a two-stage interrupted time-series design.
Synthesis in International journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Excess suicide attributable to the COVID-19 pandemic and social disparities in South Korea.Scientific reports · 2022Pooled it
- Inferring the true number of SARS-CoV-2 infections in Japan.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022Pooled it
- Understanding Japan's mortality advantage: a comparison of mortality in independent and dependent older adults in Japan and Sweden.BMC medicine · 2026Article
- Malaria amidst the COVID-19 pandemic in Gabon: an application of autoregressive integrated moving average (ARIMA) models within an interrupted time series (ITS) framework to hospital-based data.International journal of epidemiology · 2025Observational
- Stability and change in life satisfaction in Japan before and during the COVID-19 pandemic.Applied psychology. Health and well-being · 2025Article
- Increased levels of circulating cell-free DNA in COVID-19 patients with respiratory failure.Scientific reports · 2024Article
- All-cause mortality and Japan's early countermeasures.Health science reports · 2024Article
- Article
- Association of atmospheric temperature with out-of-hospital natural deaths occurrence before and during the COVID-19 pandemic in Osaka, Japan.Scientific reports · 2023Observational
- Case fatality rate considering the lag time from the onset of COVID-19 infection to related death from 2020 to 2022 in Japan.IJID regions · 2023Article
- Impact of the COVID-19 Pandemic on the Socioeconomic Inequalities in Mortality in Spanish Provinces.Journal of epidemiology and global health · 2023Article
- Social and spatial heterogeneities in COVID-19 impacts on individual's metro use: A big-data driven causality inference.Applied geography (Sevenoaks, England) · 2023Article
- Changes in cerebrovascular disease-related deaths and their location during the COVID-19 pandemic in Japan.Public health · 2023Article
- Did Depression, Schizophrenia, and Alcohol Use Increase During the COVID-19 Pandemic Even in Low-Risk Regions? An Analysis of the 2017-2020 National Health Insurance Data in Tottori Prefecture.Yonago acta medica · 2023Article
- Projections of future coronary heart disease and stroke mortality in Japan until 2040: a Bayesian age-period-cohort analysis.The Lancet regional health. Western Pacific · 2023Article
- Excess mortality during the SARS-CoV-2 pandemic in the City of Frankfurt/Main, Germany, in 2020 and 2021, adjusted for age trends and pandemic phases.GMS hygiene and infection control · 2023Article
- Article
- Time-dependent risk of COVID-19 death with overwhelmed health-care capacity in Japan, 2020-2022.BMC infectious diseases · 2022Article
- Excess mortality and the COVID-19 pandemic: causes of death and social inequalities.BMC public health · 2022Article
- Impact of the COVID-19 pandemic on critical care utilization in Japan: a nationwide inpatient database study.Journal of intensive care · 2022Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
backgroundCoronavirus disease 2019 (COVID-19) continues to be a major global health burden. This study aims to estimate the all-cause excess mortality occurring in the COVID-19 outbreak in Japan, 2020, by sex and age group.
methodsDaily time series of mortality for the period January 2015-December 2020 in all 47 prefectures of Japan were obtained from the Ministry of Health, Labour and Welfare, Japan. A two-stage interrupted time-series design was used to calculate excess mortality. In the first stage, we estimated excess mortality by prefecture using quasi-Poisson regression models in combination with distributed lag non-linear models, adjusting for seasonal and long-term variations, weather conditions and influenza activity. In the second stage, we used a random-effects multivariate meta-analysis to synthesize prefecture-specific estimates at the nationwide level.
resultsIn 2020, we estimated an all-cause excess mortality of -20 982 deaths [95% empirical confidence intervals (eCI): -38 367 to -5472] in Japan, which corresponded to a percentage excess of -1.7% (95% eCI: -3.1 to -0.5) relative to the expected value. Reduced deaths were observed for both sexes and in all age groups except those aged <60 and 70-79 years.
conclusionsAll-cause mortality during the COVID-19 outbreak in Japan in 2020 was decreased compared with a historical baseline. Further evaluation of cause-specific excess mortality is warranted.
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