Evidence map›Paper›PMID 34717921›Full record

ArticleArchives of physical medicine and rehabilitation2022

Spinal Cord Injury-Functional Index/Capacity: Responsiveness to Change Over Time.

Pamela A Kisala, Aaron J Boulton, Mary D Slavin, Matthew L Cohen, Tamra Keeney, Pengsheng Ni, Denise Tate, Allen W Heinemann, Susan Charlifue, Denise C Fyffe and 3 more

Open access · greenAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Pamela A KisalaCenter for Health Assessment Research and Translation, University of Delaware, Newark, Delaware. Electronic address: pkisala@udel.edu.
Aaron J BoultonCenter for Health Assessment Research and Translation, University of Delaware, Newark, Delaware.
Mary D SlavinDepartment of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts.
Matthew L CohenDepartment of Communication Sciences and Disorders and Center for Health Assessment Research and Translation, University of Delaware, Newark, Delaware.
Tamra KeeneyDivision of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; Mongan Institute Center for Aging and Serious Illness, Massachusetts General Hospital, Boston, Massachusetts.
Pengsheng NiDepartment of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts.
Denise TateDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, Michigan.
Allen W HeinemannShirley Ryan AbilityLab and Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Susan CharlifueCraig Hospital, Englewood, Colorado.
Denise C FyffeKessler Foundation, West Orange, New Jersey; New Jersey Medical School, Newark, New Jersey.
Elizabeth R FelixDepartment of Physical Medicine and Rehabilitation, University of Miami Miller School of Medicine, Miami, Florida.
Alan M JetteDivision of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
David S TulskyCenter for Health Assessment Research and Translation, University of Delaware, Newark, Delaware; Department of Physical Therapy, University of Delaware, Newark, Delaware; Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware.
University of Delaware · USBoston University · USMassachusetts General Hospital · USCraig Hospital · USRutgers New Jersey Medical SchoolShirley Ryan AbilityLab · USUniversity of Miami · USUniversity of Michigan–Ann Arbor · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Robert E Akins · 2013 to 2026
$60.5M
Quality of Life for SCI Clinical Trials: Development of the SCI-QOLR01HD054569 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TULSKY, DAVID SCOTT · 2007 to 2011
$3.0M
NICHD NIH HHS R01 HD054569NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

objectiveTo establish responsiveness of 3 Spinal Cord Injury-Functional Index/Capacity (SCI-FI/C) item banks in the first year after spinal cord injury (SCI).

designLongitudinal patient-reported outcomes assessment replicated through secondary analysis of an independent data set.

settingA total of 8 SCI Model Systems rehabilitation hospitals in the United States.

participantsStudy 1 participants included 184 adults with recent (≤4 months) traumatic SCI and 221 community-dwelling adults (>1 year post injury) (N=405). Study 2 participants were 418 individuals with recent SCI (≤4 months) (N=418).

interventionsIn study 1, SCI-FI/C computer adaptive tests were presented in a standardized interview format either in person or by phone call at baseline and 6-month follow-up. Responsiveness was examined by comparing 6-month changes in SCI-FI scores within and across samples (recently injured vs community-dwelling) because only the recent injury sample was expected to exhibit change over time. Effect sizes were also computed. In study 2, the study 1 results were cross-validated in a second sample with recent SCI 1 year after baseline measurement. Study 2 also compared the SCI-FI/C measures' responsiveness to that of the Self-reported Functional Measure (SRFM) and stratified results by injury diagnosis and completeness.

main outcome measuresThe SCI-FI Basic Mobility/C, Self-care/C and Fine Motor/C item banks (study 1 and study 2); Self-reported Functional Measure SRFM (study 2 only).

resultsIn study 1, changes in SCI-FI/C scores between baseline and 6-month follow-up were statistically significant (P<.01) for recently injured individuals. SCI-FI Basic Mobility/C, Self-care/C, and Fine Motor/C item banks demonstrated small to medium effect sizes in the recently injured sample. In the community-dwelling sample, all SCI-FI/C effects were negligible (ie, effect size<0.08). Study 2 results were similar to study 1. As expected, SCI-FI Basic Mobility/C and Self-care/C were responsive to change for all individuals in study 2, whereas the SCI-FI Fine Motor/C was responsive only for individuals with tetraplegia and incomplete paraplegia. The SRFM demonstrated a medium effect size for responsiveness (effect size=0.65).

conclusionsThe SCI-FI Basic Mobility/C and Self-care/C banks demonstrate adequate sensitivity to change at 6 months and 1 year for all individuals with SCI, while the SCI-FI/C Fine Motor item bank is sensitive to change in individuals with tetraplegia or incomplete paraplegia. All SCI-FI/C banks demonstrate stability in a sample not expected to change. Results provide support for the use of these measures for research or clinical use.

Indexed as

Disability EvaluationSpinal Cord InjuriesActivities of Daily LivingAdultHumansParaplegiaQuadriplegiaUnited StatesOutcomes assessment (health care)Patient reported outcome measurePsychometricsQuality of lifeRehabilitationSpinal cord injuries

Identifiers

PMID34717921
PMCPMC8810572
OpenAlexW3208126503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.