Evidence map›Paper›PMID 34717575›Full record

ArticleBMC pregnancy and childbirth2021

Syphilis testing adherence among women with livebirth deliveries: Indianapolis 2014-2016.

Opeyemi C Ojo, Janet N Arno, Guoyu Tao, Chirag G Patel, Brian E Dixon

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Uptake of prenatal syphilis screening and its determinants in Ontario, Canada: a population-based retrospective cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Opeyemi C OjoDepartment of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, 1050 Wishard Blvd., RG 5, Indianapolis, IN, 46202, USA. opolorun@iu.edu.
Janet N ArnoDivision of Infectious Disease, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Guoyu TaoDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Chirag G PatelDivision of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Brian E DixonDepartment of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, 1050 Wishard Blvd., RG 5, Indianapolis, IN, 46202, USA.

Funding

The Indiana Training Program in Public & Population Health InformaticsT15LM012502 · NLM · INDIANA UNIVERSITY INDIANAPOLIS · PI Brian E. Dixon, William F Fadel · 2017 to 2026
$4.7M
NLM NIH HHS T15 LM012502
6 · The paper itself

Abstract

backgroundThe number of congenital syphilis (CS) cases in the United States are increasing. Effective prevention of CS requires routine serologic testing and treatment of infected pregnant women. The Centers for Disease Control and Prevention (CDC) recommends testing all pregnant women at their first prenatal visit and subsequent testing at 28 weeks gestation and delivery for women at increased risk.

methodsWe conducted a cross-sectional cohort study of syphilis testing among pregnant women with a livebirth delivery from January 2014 to December 2016 in Marion County, Indiana. We extracted and linked maternal and infant data from the vital records in a local health department to electronic health records available in a regional health information exchange. We examined syphilis testing rates and factors associated with non-testing among women with livebirth delivery. We further examined these rates and factors among women who reside in syphilis prevalent areas.

resultsAmong 21260 pregnancies that resulted in livebirths, syphilis testing in any trimester, including delivery, increased from 71.7% in 2014 to 86.6% in 2016. The number of maternal syphilis tests administered only at delivery decreased from 16.6% in 2014 to 4.04% in 2016. Among women living in areas with high syphilis rates, syphilis screening rates increased from 79.6% in 2014 to 94.2% in 2016.

conclusionImprovement in prenatal syphilis screening is apparent and encouraging, yet roughly 1-in-10 women do not receive syphilis screening during pregnancy. Adherence to recommendations set out by CDC improved over time. Given increasing congenital syphilis cases, the need for timely diagnoses and prevention of transmission from mother to fetus remains a priority for public health.

Indexed as

Guideline AdherenceGuidelines as TopicAdolescentAdultCohort StudiesCross-Sectional StudiesFemaleHumansIndianaLive BirthPregnancyPregnancy Complications, InfectiousPrenatal DiagnosisSyphilisSyphilis SerodiagnosisYoung AdultCongenital syphilisPrenatal carePrenatal screeningWomen’s health

Identifiers

PMID34717575
PMCPMC8557034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.