Evidence map›Paper›PMID 34717555›Full record

ArticleBMC microbiology2021

Route of Zika virus infection in Aedes aegypti by transmission electron microscopy.

Thayane da Encarnação Sá-Guimarães, Tiago Souza Salles, Carlucio Rocha Dos Santos, Monica Ferreira Moreira, Wanderley de Souza, Lucio Ayres Caldas

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The buzz in the field: the interaction between viruses, mosquitoes, and metabolism.Frontiers in cellular and infection microbiology · 2023
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Thayane da Encarnação Sá-Guimarães *Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, CEP 21941-909, Rio de Janeiro, RJ, Brazil.
Tiago Souza Salles *Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, CEP 21941-909, Rio de Janeiro, RJ, Brazil.
Carlucio Rocha Dos SantosLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz, CEP 21040-900, Fiocruz, Rio de Janeiro, RJ, Brazil.
Monica Ferreira MoreiraDepartamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, CEP 21941-909, Rio de Janeiro, RJ, Brazil.
Wanderley de SouzaUniversidade Federal do Rio de Janeiro, Centro Nacional de Biologia Estrutural e Bioimagem (CENABIO), CEP 21941-902, Rio de Janeiro, RJ, Brazil.
Lucio Ayres CaldasInstituto de Biofísica Carlos Chagas Filho, Laboratório de Ultraestrutura Celular Hertha Meyer, Universidade Federal do Rio de Janeiro, CEP 21941-902, Rio de Janeiro, RJ, Brazil. lucio@biof.ufrj.br.
Universidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular · BRNational Institute of Science and Technology for Structural Biology and Bioimaging · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundZika fever has been a global health security threat, especially in the tropical and subtropical regions where most of the cases occur. The disease is caused by Zika virus (ZIKV), which belongs to the family Flaviviridae, genus Flavivirus. The virus is transmitted by Aedes mosquitoes, mostly by Aedes aegypti, during its blood meal. In this study we present a descriptive analysis, by transmission electron microscopy (TEM), of ZIKV infection in A. aegypti elected tissues at the 3rd day of infection. ZIKV vertical transmission experiments by oral infection were conducted to explore an offspring of natural infection.

resultsGut and ovary tissues harbored a higher number of viral particles. The ZIKV genome was also detected, by RT-qPCR technique, in the organism of orally infected female mosquitoes and in their eggs laid.

conclusionsThe data obtained suggest that the ovary is an organ susceptible to be infected with ZIKV and that virus can be transmitted from mother to a fraction of the progeny.

Indexed as

AedesAnimalsFemaleIntestinesMicroscopy, Electron, TransmissionMosquito VectorsOvaryOvumRNA, ViralVirionZika VirusZika Virus InfectionRNA, ViralAedes aegyptiEggsOvaryTransmission Electron MicroscopyVertical transmissionZika virus

Identifiers

PMID34717555
PMCPMC8557066
OpenAlexW3208770373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.