Evidence map›Paper›PMID 34716893›Full record

Trial reportWorld journal of pediatrics : WJP2021

Evaluation of a new frequency-volume chart for children with primary monosymptomatic nocturnal enuresis: a prospective, comparative study.

Jing-Jing Wang, Dong-Jie Wang, Hai-Dong Fu, De-Xuan Wang, Qing Yang, Xiao-Jie Peng, Rui Fu, Huan-Dan Yang, Rui-Feng Zhang, Xiao-Wen Wang and 20 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of pediatrics : WJP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Desmopressin for nocturnal enuresis in children.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 14 institutions in 1 country.

Jing-Jing Wang *Department of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China.
Dong-Jie Wang *Department of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China.
Hai-Dong Fu *Department of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China.
De-Xuan WangDepartment of Nephrology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Qing YangDepartment of Nephrology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Xiao-Jie PengDepartment of Nephrology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Rui FuDepartment of Nephrology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Huan-Dan YangDepartment of Nephrology, Xuzhou Children's Hospital, Xuzhou Medical University, Xuzhou, China.
Rui-Feng ZhangDepartment of Nephrology, Xuzhou Children's Hospital, Xuzhou Medical University, Xuzhou, China.
Xiao-Wen WangDepartment of Nephrology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jiang-Wei LuanDepartment of Nephrology, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fei ZhaoDepartment of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Qiu-Xia ChenDepartment of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Fang-Fang LiangDepartment of Rheumatology, Shenzhen Children's Hospital, Shenzhen, China.
Lu CaoDepartment of Pediatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jian-Jiang ZhangDepartment of Pediatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Ying-Jie LiDepartment of Nephrology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Yang DongDepartment of Nephrology, Anhui Provincial Children's Hospital, Hefei, China.
Hui-Mei HuangDepartment of Nephrology, The Affiliated Children Hospital of Xi'an Jiaotong University, Xi'an, China.
Ying BaoDepartment of Nephrology, The Affiliated Children Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiao-Yu ShenDepartment of Nephrology, Shanghai Children's Medical Center, Shanghai, China.
Wei ZhouDepartment of Nephrology, Shanghai Children's Medical Center, Shanghai, China.
Guang-Hai CaoDepartment of Nephrology and Rheumatology, Children's Hospital Affiliated to ZhengZhou University, Henan Children's Hospital, ZhengZhou Children's Hospital, ZhengZhou, China.
Cui-Hua LiuDepartment of Nephrology and Rheumatology, Children's Hospital Affiliated to ZhengZhou University, Henan Children's Hospital, ZhengZhou Children's Hospital, ZhengZhou, China.
Yan-Yan JinDepartment of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China.
Mei-Lin MaMedical Affairs Department, Ferring Pharmaceuticals (Asia) Company Limited, Shanghai, China.
Li JiangMarketing Department, Ferring Pharmaceuticals (Asia) Company Limited, Shanghai, China.
Qian ShenDepartment of Nephrology, The Children's Hospital of Fudan University, Shanghai, China.
Hong XuDepartment of Nephrology, The Children's Hospital of Fudan University, Shanghai, China.
Jian-Hua MaoDepartment of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China. maojh88@zju.edu.cn.ORCID http://orcid.org/0000-0002-6076-3806
Children's Hospital of Zhejiang University · CNWenzhou Medical University · CNChildren's Hospital of Fudan University · CNFirst Affiliated Hospital of Zhengzhou University · CNJiangxi Provincial Children's Hospital · CNSecond Affiliated Hospital of Nanjing Medical University · CNShanghai Children's Medical Center · CNWuhan Children's Hospital · CNXi’an Children’s Hospital · CNXuzhou Medical College · CNZhengzhou Children's Hospital · CNAnhui Provincial Children's Hospital · CNGuangzhou Women and Children Medical Center · CNShenzhen Children's Hospital · CN

Funding

Key Research and Development Program of Jiangxi Province 2019C03028National Natural Foundation of China 81770710The Major Projects Jointly Constructed by the Zhejiang Province and national health commission WKJ-ZJ-1908The Natural Science Foundation of Zhejiang Province LQ18H050001
6 · The paper itself

Abstract

introductionTo improve compliance with voiding diaries in children with primary monosymptomatic nocturnal enuresis (PMNE), a new modified 3-day weekend frequency-volume chart (FVC) was designed, and the compliance and validity of this modified FVC was evaluated by comparing with the International Children's Continence Society (ICCS) recommended voiding diary.

methodsA total of 1200 patients with PMNE were enrolled in the study from 13 centers in China and were randomly assigned to record this modified FVC or the ICCS-recommended voiding diary. The primary outcome measure was the compliance, assessed by comparing the completing index and the quality score of diaries between two groups. The secondary outcome measure was the validity, evaluated by comparing the constituent of subtypes, micturition parameters and response rate to desmopressin.

resultsAmong the 1200 participants enrolled in the study, 447 patients completed the ICCS-recommended voiding diary and 469 completed the modified diary. The diurnal completing index and the quality score of the modified FVC group were better than those of the ICCS group. In addition, there was no significant difference between these two groups in the subtype classification, or in the response rate to desmopressin.

conclusionsThe modified FVC could be applied to obtain the voiding characteristics of children with PMNE as the ICCS-recommended voiding diary does and offers a reasonable and better choice for children with PMNE from the unselected population in the future.

Indexed as

Nocturnal EnuresisChildChinaHumansProspective StudiesChildrenComplianceNocturnal enuresisVoiding diary

Identifiers

PMID34716893
OpenAlexW3210960836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.