Evidence map›Paper›PMID 34716815›Full record

ArticleMikrochimica acta2021

Carbon nanodot-based electrogenerated chemiluminescence biosensor for miRNA-21 detection.

Laura Gutiérrez-Gálvez, Tania García-Mendiola, Cristina Gutiérrez-Sánchez, Tamara Guerrero-Esteban, Cristina García-Diego, Irene Buendía, M Laura García-Bermejo, Félix Pariente, Encarnación Lorenzo

Open access · hybridAbstract read
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  3. Article
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  5. Review
  6. MoSBiosensors · 2023
    Article
  7. Molecular Diagnosis and Cancer Prognosis-A Concise Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Laura Gutiérrez-GálvezDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain.
Tania García-MendiolaDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain. tania.garcia@uam.es.
Cristina Gutiérrez-SánchezDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain. cristina.gutierrezs@uam.es.ORCID http://orcid.org/0000-0001-8011-6211
Tamara Guerrero-EstebanDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain.
Cristina García-DiegoInstituto de Catálisis y Petroleoquímica, Consejo Superior de Investigaciones Científicas, C/Marie Curie 2, 28049, Madrid, Spain.
Irene BuendíaBiomarkers and Therapeutic Targets Group and Core Facility, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Spanish Renal Research Network (REDinREN), Madrid, Spain.
M Laura García-BermejoBiomarkers and Therapeutic Targets Group and Core Facility, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Spanish Renal Research Network (REDinREN), Madrid, Spain.
Félix ParienteDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain.
Encarnación LorenzoDepartment of Analytical Chemistry and Instrumental Analysis, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain.
Universidad Autónoma de Madrid · ESSpanish Clinical Research Network · ESConsejo Superior de Investigaciones Científicas · ESIMDEA Nanoscience · ESMadrid Institute for Advanced Studies · ES

Funding

DOPAMINE TRANSPORTER: CDNA AND FUNCTIONF32DA005435 · NIDA · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI COREY, JANIS L · 1991 to 1993
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Comunidad de Madrid 2017-T1/BIO-5435Comunidad de Madrid MAD2D-CM ProgramComunidad de Madrid NANOAVANSENSComunidad de Madrid S2013/MIT-3007Comunidad de Madrid S2013/MIT-3029Ministerio de Ciencia, Innovación y Universidades CTQ2014-53334-C2-1-RMinisterio de Ciencia, Innovación y Universidades CTQ2015-71955-REDT (ELECTROBIONET)Ministerio de Ciencia, Innovación y Universidades MAT2015-71879-P
6 · The paper itself

Abstract

A simple carbon nanodot-based electrogenerated chemiluminescence biosensor is described for sensitive and selective detection of microRNA-21 (miRNA-21), a biomarker of several pathologies including cardiovascular diseases (CVDs). The photoluminescent carbon nanodots (CNDs) were obtained using a new synthesis method, simply by treating tiger nut milk in a microwave reactor. The synthesis is environmentally friendly, simple, and efficient. The optical properties and morphological characteristics of the CNDs were exhaustively investigated, confirming that they have oxygen and nitrogen functional groups on their surfaces and exhibit excitation-dependent fluorescence emission, as well as photostability. They act as co-reactant agents in the anodic electrochemiluminescence (ECL) of [Ru(bpy)

Indexed as

Biosensing TechniquesCarbonCoordination ComplexesElectrochemical TechniquesElectrodesGoldHeart FailureHumansImmobilized Nucleic AcidsLimit of DetectionLuminescent AgentsLuminescent MeasurementsMaleMicroRNAsNucleic Acid HybridizationOligodeoxyribonucleotidesCarbonCoordination ComplexesGoldImmobilized Nucleic AcidsLuminescent AgentsMicroRNAsMIRN21 microRNA, humanOligodeoxyribonucleotidesRuthenium Compoundstris(2,2-bipyridine)-ruthenium(II)Carbon nanomaterialsECL biosensorGreen chemistry synthesisRNA detection

Identifiers

PMID34716815
PMCPMC8557186
OpenAlexW3208572221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.