ArticleHuman brain mapping2022
Visuomotor brain network activation and functional connectivity among individuals with autism spectrum disorder.
Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Execution, imitation and observation of naturalistic actions in autistic children and adolescents: a systematic review of fMRI studies.Frontiers in human neuroscience · 2026Pooled it
- Episodic memory impairment and its influencing factors in individuals with autism spectrum disorder: systematic review and meta-analysis.European archives of psychiatry and clinical neuroscience · 2025Pooled it
- Action execution and observation in autistic adults: A systematic review of fMRI studies.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Association Between Toe Walking and Repetitive Behaviors in Children with Autism Spectrum Disorder: A Cross-Sectional Phenotypic Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Cerebellar Contributions to Cerebral Connectivity in Severe Mental Illness: A Developmental Cascade and Predictive-Modeling Framework with Autistic Disorder as the Focal Case.Brain sciences · 2026Review
- Gait variability development in autistic individuals across childhood and adulthood.Research square · 2026Article
- Atypical Visually Guided Precision Grip Control in Middle-Aged and Older Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026Article
- The association between motor coordination impairment and altered functional connectivity among autistic children.Frontiers in pediatrics · 2026Article
- Intergenerational neuroimaging's present and future: Considering sex as a biological variable to enhance knowledge of brain development through parent-offspring similarity.Developmental cognitive neuroscience · 2025Review
- Mapping Resting-State Brain Functional Specialization to Neurotransmitter Profiles in Autism Spectrum Disorder.CNS neuroscience & therapeutics · 2025Article
- Distinct and shared intrinsic resting-state functional networks in children with idiopathic autism spectrum disorder and fragile X syndrome.Molecular psychiatry · 2025Article
- Examining Transdiagnostic Patterns of Motor Differences: Preliminary Findings From the Consortium for Motor Behavior in Neurodivergence (COMBINE).Journal of autism and developmental disorders · 2025Article
- Autistic traits relate to speed/accuracy trade-off but not statistical learning and updating.Scientific reports · 2025Article
- Visual feedback and motor memory contributions to sustained motor control deficits in autism spectrum disorder across childhood and into adulthood.Journal of neurodevelopmental disorders · 2025Article
- Functional near-infrared spectroscopy characteristics in children with autism spectrum disorder under animated video modeling therapy.Frontiers in neurology · 2025Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Symmetric bimanual coordination discrepancy and activities of daily living in individuals with autism spectrum disorder.International journal of developmental disabilities · 2025Article
- Alterations in the white matter fiber tracts of preschool-aged children with autism spectrum disorder: an automated fiber quantification study.Quantitative imaging in medicine and surgery · 2024Article
- Changes in effective connectivity during the visual-motor integration tasks: a preliminary f-NIRS study.Behavioral and brain functions : BBF · 2024Article
- Microstructural neural correlates of maximal grip strength in autistic children: the role of the cortico-cerebellar network and attention-deficit/hyperactivity disorder features.Frontiers in integrative neuroscience · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Sensorimotor abnormalities are common in autism spectrum disorder (ASD) and predictive of functional outcomes, though their neural underpinnings remain poorly understood. Using functional magnetic resonance imaging, we examined both brain activation and functional connectivity during visuomotor behavior in 27 individuals with ASD and 30 typically developing (TD) controls (ages 9-35 years). Participants maintained a constant grip force while receiving visual feedback at three different visual gain levels. Relative to controls, ASD participants showed increased force variability, especially at high gain, and reduced entropy. Brain activation was greater in individuals with ASD than controls in supplementary motor area, bilateral superior parietal lobules, and contralateral middle frontal gyrus at high gain. During motor action, functional connectivity was reduced between parietal-premotor and parietal-putamen in individuals with ASD compared to controls. Individuals with ASD also showed greater age-associated increases in functional connectivity between cerebellum and visual, motor, and prefrontal cortical areas relative to controls. These results indicate that visuomotor deficits in ASD are associated with atypical activation and functional connectivity of posterior parietal, premotor, and striatal circuits involved in translating sensory feedback information into precision motor behaviors, and that functional connectivity of cerebellar-cortical sensorimotor and nonsensorimotor networks show delayed maturation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.