Evidence map›Paper›PMID 34716570›Full record

ArticleAging clinical and experimental research2022

Atrial fibrillation and COVID-19 in older patients: how disability contributes to shape the risk profile. An analysis of the GeroCovid registry.

Stefano Fumagalli, Caterina Trevisan, Susanna Del Signore, Giulia Pelagalli, Carlo Fumagalli, Andrea Herbst, Stefano Volpato, Pietro Gareri, Enrico Mossello, Alba Malara and 9 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04379440 (Geriatric Population COVID-19 Syndromic Characteristics and Clinical Outcomes), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04379440 unknown statusnot on this map

Geriatric Population COVID-19 Syndromic Characteristics and Clinical Outcomes: a Multi-setting, Multi-domain Observational Study (GEROCOVID Observational)

Typeobservational_patient_registrySponsorRaffaele Antonelli IncalziRan2020 to 2020Enrolled1,500ConditionsCOVID-19
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. COVID-19 HEART unveiling as atrial fibrillation: pathophysiology, management and future directions for research.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Review
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 10 institutions in 3 countries.

Stefano FumagalliGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy. stefano.fumagalli@unifi.it.ORCID http://orcid.org/0000-0002-6950-3875
Caterina TrevisanGeriatrics Division, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Susanna Del SignoreBluecompanion Ltd, London, UK.
Giulia PelagalliGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy.
Carlo FumagalliGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy.
Andrea HerbstGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy.
Stefano VolpatoDepartment of Medical Science, Section of Internal and Cardiorespiratory Medicine, University of Ferrara, Ferrara, Italy.
Pietro GareriCenter for Cognitive Disorders and Dementia-Catanzaro Lido, ASP Catanzaro, Catanzaro, Italy.
Enrico MosselloGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy.
Alba MalaraScientific Committee of National Association of Third Age Residences (ANASTE) Calabria, Lamezia Terme (Catanzaro), Italy.
Fabio MonzaniGeriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Chukwuma OkoyeGeriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Alessandra CoinGeriatrics Division, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Giuseppe BellelliSchool of Medicine and Surgery, Acute Geriatric Unit, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy.
Gianluca ZiaBluecompanion Ltd, London, UK.
Andrea UngarGeriatric Intensive Care Unit and Geriatric Arrhythmia Unit, Department of Experimental and Clinical Medicine, University of Florence and AOU Careggi, Largo Brambilla, 3, 50134, Florence, Italy.
Anette Hylen RanhoffDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Raffaele Antonelli IncalziUnit of Geriatrics, Department of Medicine, Campus Bio Medico University and Teaching Hospital, Rome, Italy.
GeroCovid Working Group
University of Florence · ITUniversity of Padua · ITUniversity of Pisa · ITAccademia di Belle Arti di Catanzaro · ITAzienda Ospedaliero-Universitaria Careggi · ITUniversità Campus Bio-Medico · ITUniversity of Bergen · NOUniversity of Ferrara · ITUniversity of Milano-Bicocca · ITUniversity of the Third Age · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsAtrial fibrillation (AF) is often complicated by disabling conditions in the elderly. COVID-19 has high mortality in older people. This study aimed at evaluating the relationship of pre-infection AF with characteristics and survival of older COVID-19 patients.

methodsWe retrospectively analyzed inpatients aged ≥ 60 years enrolled in GeroCovid Observational, a multicenter registry endorsed by the Italian and the Norwegian Societies of Gerontology and Geriatrics. Pre-COVID-19 sociodemographic, functional, and medical data were systematically collected, as well as in-hospital mortality.

resultsBetween March and June 2020, 808 COVID-19 subjects were enrolled (age 79 ± 9 years; men 51.7%). The prevalence of AF was 21.8%. AF patients were older (82 ± 8 vs. 77 ± 9 years, p < 0.001), had a higher CHA

conclusionsAF is frequent in older patients with COVID-19, in whom it associates with clinical complexity and high mortality. Pre-infection disability shapes the prognosis of this extremely vulnerable segment of hospitalized subjects. CLINICAL

trial registrationGeroCovid Observational was registered at www.clinicaltrials.gov (NCT04379440).

Indexed as

Atrial FibrillationCOVID-19StrokeAgedAged, 80 and overAnticoagulantsHumansMaleRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSARS-CoV-2AnticoagulantsAtrial fibrillationCOVID-19DisabilityOlder patientsOral anticoagulantsPrognosis

Identifiers

PMID34716570
PMCPMC8556143
OpenAlexW3208458289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.