Evidence map›Paper›PMID 34716386›Full record

ArticleScientific reports2021

Chronic kidney disease and pregnancy outcomes.

Jan Dvořák, Michal Koucký, Eva Jančová, Marek Mysliveček, Vladimír Tesař, Antonín Pařízek

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Outcome of neonates born to mothers with chronic kidney disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jan DvořákDepartment of Obstetrics and Gynaecology, General University Hospital in Prague and First Faculty of Medicine, Charles University, Apolinářská 18, 128 08, Prague 2, Czech Republic.
Michal KouckýDepartment of Obstetrics and Gynaecology, General University Hospital in Prague and First Faculty of Medicine, Charles University, Apolinářská 18, 128 08, Prague 2, Czech Republic.
Eva JančováDepartment of Nephrology, General University Hospital in Prague and First Faculty of Medicine, Charles University, U Nemocnice 499/2, 128 08, Prague 2, Czech Republic. eva.jancova@vfn.cz.
Marek MyslivečekDepartment of Nephrology, General University Hospital in Prague and First Faculty of Medicine, Charles University, U Nemocnice 499/2, 128 08, Prague 2, Czech Republic.
Vladimír TesařDepartment of Nephrology, General University Hospital in Prague and First Faculty of Medicine, Charles University, U Nemocnice 499/2, 128 08, Prague 2, Czech Republic.
Antonín PařízekDepartment of Obstetrics and Gynaecology, General University Hospital in Prague and First Faculty of Medicine, Charles University, Apolinářská 18, 128 08, Prague 2, Czech Republic.
Charles University · CZGeneral University Hospital in Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy complicated by CKD is currently not fully understood topic. Outcome of pregnancy in patients with CKD is related to impaired glomerular filtration rate and the degree of proteinuria. In our study we evaluated the association of serum creatinine level and proteinuria with both maternal and fetal outcomes in the cohort of 84 pregnant patients with CKD. In CKD group we confirmed negative correlation of highest serum creatinine level in pregnancy to fetal weight (p value < 0.001) and gestation period (p value < 0.001). Likewise, negative correlation of preconception serum creatinine to fetal weight (p value < 0.001) and gestation period (p value 0.002). Negative correlation of proteinuria to gestation period (p value < 0.001) and fetal weight (p value < 0.001) was also demonstrated. CKD is serious risk factor for pregnancy outcome. Proteinuria and serum creatinine level should be examined before pregnancy and regularly monitored during pregnancy. Higher serum creatinine levels and higher proteinuria predispose to shorter gestation period and lower birth weight of the neonate.

Indexed as

Pregnancy ComplicationsAdultCohort StudiesCreatinineFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeProteinuriaRenal Insufficiency, ChronicRisk FactorsCreatinine

Identifiers

PMID34716386
PMCPMC8556278
OpenAlexW3208684628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.