ArticleScientific reports2021
Transcriptomic analysis of Rhodococcus opacus R7 grown on polyethylene by RNA-seq.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 70 citations in OpenAlex.
- Exploring the role of oxidative defects in polyethylene binding and degradation by a Rhodococcus opacus R7 multicopper oxidase: a computational perspective.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026Article
- Cell Disruption and RNA Extraction fromInternational journal of molecular sciences · 2026Article
- Biodegradation of components from an oxidized polyethylene by aApplied and environmental microbiology · 2026Article
- Genome-to-function integrated exploration of polyethylene biodegradation by Rhodococcus opacus R7.BMC microbiology · 2026Article
- Enzymatic activity screening in marine bacteria exposed to oxo-polyethylene in artificial marine microcosms.BMC research notes · 2026Article
- Harnessing bacterial power and omics technologies for sustainable plastic waste biodegradation.Biodegradation · 2026Review
- Advances in polyethylene biodegradation and bioconversion: Microbial, enzymatic, and biotechnological insights.Engineering microbiology · 2026Review
- Functional and genomic characterization of polyethylene degrading yeast Meyerozyma carpophila M6.0.2 isolated from marine plastic debris in East Java Indonesia.Scientific reports · 2025Article
- Molecular-Genetic Research ofMolecules (Basel, Switzerland) · 2025Article
- Microbial degradation of a widely used model polyethylene is restricted to medium- and long-chain alkanes and their oxidized derivatives.The ISME journal · 2025Article
- Omic-driven strategies to unveil microbiome potential for biodegradation of plastics: a review.Archives of microbiology · 2024Review
- Enterobacter cloacae-mediated polymer biodegradation: in-silico analysis predicts broad spectrum degradation potential by Alkane monooxygenase.Biodegradation · 2024Article
- Metagenomic analyses of a consortium for the bioremediation of hydrocarbons polluted soils.AMB Express · 2024Article
- Assessing microbial plastic degradation requires robust methods.Microbial biotechnology · 2024Article
- Insights into polyethylene biodegradative fingerprint ofFrontiers in bioengineering and biotechnology · 2024Article
- Exploring untapped bacterial communities and potential polypropylene-degrading enzymes from mangrove sediment through metagenomics analysis.Frontiers in microbiology · 2024Article
- Global perspectives on the biodegradation of LDPE in agricultural systems.Frontiers in microbiology · 2024Review
- Polyethylene Degradation by aEnvironmental science & technology · 2023Article
- A computational approach to optimising laccase-mediated polyethylene oxidation through carbohydrate-binding module fusion.BMC biotechnology · 2023Article
- Gut microbiome of mealworms (Tenebrio molitor Larvae) show similar responses to polystyrene and corn straw diets.Microbiome · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plastic waste management has become a global issue. Polyethylene (PE) is the most abundant synthetic plastic worldwide, and one of the most resistant to biodegradation. Indeed, few bacteria can degrade polyethylene. In this paper, the transcriptomic analysis unveiled for the first time Rhodococcus opacus R7 complex genetic system based on diverse oxidoreductases for polyethylene biodegradation. The RNA-seq allowed uncovering genes putatively involved in the first step of oxidation. In-depth investigations through preliminary bioinformatic analyses and enzymatic assays on the supernatant of R7 grown in the presence of PE confirmed the activation of genes encoding laccase-like enzymes. Moreover, the transcriptomic data allowed identifying candidate genes for the further steps of short aliphatic chain oxidation including alkB gene encoding an alkane monooxygenase, cyp450 gene encoding cytochrome P450 hydroxylase, and genes encoding membrane transporters. The PE biodegradative system was also validated by FTIR analysis on R7 cells grown on polyethylene.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.