ArticleNature communications2021
Structural basis for high selectivity of a rice silicon channel Lsi1.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 55 citations in OpenAlex.
- Silicon at the Soil-Plant-Microbiome Interface: Rhizospheric Reconfiguration and Crop Resilience to Environmental Stresses.Plants (Basel, Switzerland) · 2026Review
- Innovations in Silicon Transport Shaped the Rise of Biosilicification and Skeletal Evolution in Sponges.Molecular biology and evolution · 2026Article
- Cryo-EM structure of human AQP11 reveals a trimeric architecture with a large pore.Science advances · 2026Article
- Evolutionary and Structural Analysis of the Aquaporin Gene Family in Rice.Plants (Basel, Switzerland) · 2025Review
- Dual stimuli-responsive prodrug co-delivery nanosystem of salicylic acid and bioavailable silicon for long-term immunity in plant.Journal of nanobiotechnology · 2025Article
- OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.Nature methods · 2024Article
- Tissue-specific deposition, speciation and transport of antimony in rice.Plant physiology · 2024Article
- Structural assessment of OsNIP2;1 highlighted critical residues defining solute specificity and functionality of NIP class aquaporins.Journal of advanced research · 2024Article
- The Physiological and Molecular Mechanisms of Silicon Action in Salt Stress Amelioration.Plants (Basel, Switzerland) · 2024Review
- Analysis ofPlants (Basel, Switzerland) · 2023Article
- Polar localization of a rice silicon transporter requires isoleucine at both C- and N-termini as well as positively charged residues.The Plant cell · 2023Article
- Correction of rhodopsin serial crystallography diffraction intensities for a lattice-translocation defect.Acta crystallographica. Section D, Structural biology · 2023Article
- The structure, function and expression analysis of the nodulin 26-like intrinsic protein subfamily of plant aquaporins in tomato.Scientific reports · 2022Article
- Structure and function of a silicic acid channel Lsi1.Frontiers in plant science · 2022Review
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silicon (Si), the most abundant mineral element in the earth's crust, is taken up by plant roots in the form of silicic acid through Low silicon rice 1 (Lsi1). Lsi1 belongs to the Nodulin 26-like intrinsic protein subfamily in aquaporin and shows high selectivity for silicic acid. To uncover the structural basis for this high selectivity, here we show the crystal structure of the rice Lsi1 at a resolution of 1.8 Å. The structure reveals transmembrane helical orientations different from other aquaporins, characterized by a unique, widely opened, and hydrophilic selectivity filter (SF) composed of five residues. Our structural, functional, and theoretical investigations provide a solid structural basis for the Si uptake mechanism in plants, which will contribute to secure and sustainable rice production by manipulating Lsi1 selectivity for different metalloids.
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