ArticleProceedings of the National Academy of Sciences of the United States of America2021
Live agent preference and social action monitoring in the macaque mid-superior temporal sulcus region.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 20 citations in OpenAlex.
- Translating functional brain activity between humans and monkeys.bioRxiv : the preprint server for biology · 2026Article
- Computational origins of cortical brain circuits for social cognition.Nature reviews. Neuroscience · 2026Review
- Mid-superior temporal sulcus encodes spatial context and behavioral state in freely moving macaques.bioRxiv : the preprint server for biology · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Understanding the Brain as a Mentalizing Machine with a Symbol Grounding Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Differential and Temporally Dynamic Involvement of Primate Amygdala Nuclei in Face Reality and Reward Information Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Development of Socially Directed Attention: A Functional Magnetic Resonance Imaging Study in Infant Monkeys.Journal of cognitive neuroscience · 2024Article
- The big mixup: Neural representation during natural modes of primate visual behavior.Current opinion in neurobiology · 2024Review
- Dynamic spatial representation of self and others' actions in the macaque frontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A frontopolar-temporal circuit determines the impact of social information in macaque decision making.Neuron · 2024Article
- Specialized Networks for Social Cognition in the Primate Brain.Annual review of neuroscience · 2023Review
- Tuning in to real-time social interactions in macaques.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Social connections predict brain structure in a multidimensional free-ranging primate society.Science advances · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Mentalizing, the ability to infer the mental states of others, is a cornerstone of adaptive social intelligence. While functional brain mapping of human mentalizing has progressed considerably, its evolutionary signature in nonhuman primates remains debated. The discovery that the middle part of the macaque superior temporal sulcus (mid-STS) region has a connectional fingerprint most similar to the human temporoparietal junction (TPJ)-a crucial node in the mentalizing network-raises the possibility that these cortical areas may also share basic functional properties associated with mentalizing. Here, we show that this is the case in aspects of a preference for live social interactions and in a theoretical framework of predictive coding. Macaque monkeys were trained to perform a turn-taking choice task with another real monkey partner sitting directly face-to-face or a filmed partner appearing in prerecorded videos. We found that about three-fourths of task-related mid-STS neurons exhibited agent-dependent activity, most responding selectively or preferentially to the partner's action. At the population level, activities of these partner-type neurons were significantly greater under live-partner compared to video-recorded-partner task conditions. Furthermore, a subset of the partner-type neurons responded proactively when predictions about the partner's action were violated. This prediction error coding was specific to the action domain; almost none of the neurons signaled error in the prediction of reward. The present findings highlight unique roles of the macaque mid-STS at the single-neuron level and further delineate its functional parallels with the human TPJ in social cognitive processes associated with mentalizing.
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