ArticleProceedings of the National Academy of Sciences of the United States of America2021
Power spectra reveal distinct BOLD resting-state time courses in white matter.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- A Distinct Second Spectral Peak in White Matter BOLD Signals: Mathematical Modeling, Spatial Distribution and Age-Related Evolution.Research square · 2026Article
- White-Matter BOLD Encoding Beyond Marginal Connectivity.bioRxiv : the preprint server for biology · 2026Article
- Developmental changes of the white matter functional connectome.Molecular psychiatry · 2026Article
- The nature and interpretation of BOLD signals in white matter - A review.Magnetic resonance imaging · 2026Review
- Body weight-related alterations in white matter functional connectivity in children: An fMRI study.BMC neurology · 2026Article
- Aperiodic parameters of the fMRI power spectrum associate with preterm birth and neonatal age.Communications biology · 2026Article
- Functional contrast across the gray-white matter boundary.Nature communications · 2025Article
- White matter dysfunction in Alzheimer's disease is associated with disease-related transcriptomic signatures.Communications biology · 2025Article
- Myelination selectively modulates BOLD signal in white matter.Research square · 2025Article
- White Matter-Gray Matter Correlation Analysis Based on White Matter Functional Gradient.Brain sciences · 2024Article
- Cortical activations in cognitive task performance at multiple frequency bands.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Characteristic BOLD signals are detectable in white matter of the spinal cord at rest and after a stimulus.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Connectivity gradients in spontaneous brain activity at multiple frequency bands.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Intracranial electrophysiological and structural basis of BOLD functional connectivity in human brain white matter.Nature communications · 2023Article
- Changes in white matter functional networks across late adulthood.Frontiers in aging neuroscience · 2023Article
- Functional Connectivity of White Matter and Its Association with Sleep Quality.Nature and science of sleep · 2023Article
- Changes in white matter functional networks during wakefulness and sleep.Human brain mapping · 2022Article
- Detection of functional activity in brain white matter using fiber architecture informed synchrony mapping.NeuroImage · 2022Article
- Article
- Anomalous and heterogeneous characteristics of the BOLD hemodynamic response function in white matter.Cerebral cortex communications · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
Accurate characterization of the time courses of blood-oxygen-level-dependent (BOLD) signal changes is crucial for the analysis and interpretation of functional MRI data. While several studies have shown that white matter (WM) exhibits distinct BOLD responses evoked by tasks, there have been no comprehensive investigations into the time courses of spontaneous signal fluctuations in WM. We measured the power spectra of the resting-state time courses in a set of regions within WM identified as showing synchronous signals using independent components analysis. In each component, a clear separation between voxels into two categories was evident, based on their power spectra: one group exhibited a single peak, and the other had an additional peak at a higher frequency. Their groupings are location specific, and their distributions reflect unique neurovascular and anatomical configurations. Importantly, the two categories of voxels differed in their engagement in functional integration, revealed by differences in the number of interregional connections based on the two categories separately. Taken together, these findings suggest WM signals are heterogeneous in nature and depend on local structural-vascular-functional associations.
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