Evidence map›Paper›PMID 34716106›Full record

Trial reportBrazilian journal of otorhinolaryngology

The effect of honey on post-tonsillectomy pain relief: a randomized clinical trial.

Azmeilia Syafitri Lubis, H R Yusa Herwanto, Andrina Y M Rambe, Delfitri Munir, Harry A Asroel, Taufik Ashar, Aznan Lelo

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Azmeilia Syafitri LubisUniversitas Sumatera Utara, Faculty of Medicine, Department of Otorhinolaryngology, Medan, Indonesia. Electronic address: azmeilialubis@gmail.com.
H R Yusa HerwantoUniversitas Sumatera Utara, Faculty of Medicine, Department of Otorhinolaryngology, Medan, Indonesia.
Andrina Y M RambeUniversitas Sumatera Utara, Faculty of Medicine, Department of Otorhinolaryngology, Medan, Indonesia.
Delfitri MunirUniversitas Sumatera Utara, Faculty of Medicine, Department of Otorhinolaryngology, Medan, Indonesia.
Harry A AsroelUniversitas Sumatera Utara, Faculty of Public Health, Department of Environmental Health, Medan, Indonesia.
Taufik AsharUniversitas Sumatera Utara, Faculty of Public Health, Department of Environmental Health, Medan, Indonesia.
Aznan LeloUniversitas Sumatera Utara, Faculty of Medicine, Department of Pharmacology, Medan, Indonesia.
Universitas Sumatera Utara · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to evaluate the effects of honey on the incidence of post-operative pain in patients undergoing tonsillectomy.

methodsThis study is a double-blind and randomized controlled trial design. Twenty-four adult male patients underwent tonsillectomy surgery and were randomized assigned into three groups consist of honey group, placebo group, and control group. All subjects were given standard analgesia and antibiotics, also honey for the honey group and placebo for the placebo group, and only standard post-operative regimens for the control group. This study used silk-cotton tree or kapok tree honey (Ceiba pentandra). Honey was used by gargling every six hours for ten days. Likewise, the same method was applied in the placebo group. Pain scale was assessed for ten days using the Visual Analogue Scale questionnaire, and the frequency of analgesic drugs was recorded on days 1, 2, 4, 7, and 10.

resultHoney group showed significantly higher pain reduction when compared to placebo and control groups, with a significant reduction in the pain scale on day 1, 2, 4, 7 and 10 (p = 0.034; p = 0.003; p < 0.001; p = 0.001; p = 0.001) gradually; Significant differences were also observed in analgesic use, especially on day 2, 4 and 7 (p = 0.028; p = 0.001; p = 0.003).

conclusionsAdministration of Kapok tree honey (C. pentandra) after tonsillectomy might reduce post-operative pain and reduce the need for analgesia. Therefore, honey can be considered a complementary medicine and can be administered routinely as adjunctive therapy for post-operative patients.

Indexed as

HoneyTonsillectomyAdultAnti-Bacterial AgentsDouble-Blind MethodHumansPostoperative PainAnti-Bacterial AgentsComplementary therapyHoneyPainPain reliefTonsillectomy

Identifiers

PMID34716106
PMCPMC9874356
OpenAlexW3207793807

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.