ArticleVirology journal2021
Epidemiologic and clinical characteristics of human bocavirus infection in infants and young children suffering with community acquired pneumonia in Ningxia, China.
Article in Virology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 31 citations in OpenAlex.
- Etiology and Clinical Manifestations of Acute Respiratory Infections in Pediatric Patients: A Retrospective Study in Moscow, Russia.Diseases (Basel, Switzerland) · 2026Article
- Disease burden and outcomes of pediatric human bocavirus mono-infections: a three-year retrospective study from a large tertiary cohort.BMC infectious diseases · 2026Article
- Tracking the occurrence and fate of human bocavirus 2 in municipal wastewater from a small city.Molecular biology reports · 2026Article
- Epidemiology and lagged climatic drivers of pediatric viral lower respiratory tract infections in Tianjin, China (2023-2025).Frontiers in cellular and infection microbiology · 2026Article
- Human bocavirus: As an emerging respiratory pathogen.World journal of virology · 2025Review
- Clinical characteristics and risk factors of severe bocavirus-positive pneumonia in children and a literature review.Pediatric discovery · 2025Article
- Early and rapid prediction of severe Human Bocavirus 1 pneumonia in children: an age-stratified Nomogram Model based on admission data.European journal of pediatrics · 2025Article
- Molecular detection and characterization of human bocavirus in environmental waters in Thailand from 2020 to 2022.One health (Amsterdam, Netherlands) · 2025Article
- Clinical characteristics and risk factors of severe pneumonia caused by human bocavirus in children.BMC infectious diseases · 2025Article
- Molecular epidemiological characterization of human bocavirus (HBoV) in acute respiratory infection (ARI) patients in Yucheng, China.Frontiers in public health · 2025Article
- Human Bocavirus Circulating in Patients with Acute Gastroenteritis in Taiwan, 2018-2022.Viruses · 2024Article
- Article
- Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses.Microbiology spectrum · 2024Article
- Analysis of a Cohort of 165 Pediatric Patients with Human Bocavirus Infection and Comparison between Mono-Infection and Respiratory Co-Infections: A Retrospective Study.Pathogens (Basel, Switzerland) · 2024Article
- Viral Coinfection of Children Hospitalized with Severe Acute Respiratory Infections during COVID-19 Pandemic.Biomedicines · 2023Article
- Human Bocavirus in Childhood: A True Respiratory Pathogen or a "Passenger" Virus? A Comprehensive Review.Microorganisms · 2023Review
- The role of human bocavirus as an agent of community-acquired pneumonia in children under 5 years of age in Fortaleza, Ceará (Northeast Brazil).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Comparison of the clinical features of human bocavirus and metapneumovirus lower respiratory tract infections in hospitalized children in Suzhou, China.Frontiers in pediatrics · 2022Article
- Epidemiologic and clinical characteristics of human bocavirus infection in children hospitalized for acute respiratory tract infection in Qingdao, China.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPneumonia has a high incidence rate and is a major cause of mortality in children, mostly community-acquired pneumonia (CAP). Human bocavirus (HBoV), since it first identified in 2005, has been repeatedly associated with respiratory tract infections. Nevertheless, the role and related information of HBoV as a pathogen of CAP has not been fulfilled. Here our study is to assess the epidemiological and clinical features in HBoV-positive children with CAP.
methodsA total of 878 secretions of lower respiratory samples were obtained, multiplex PCR was used to detect HBoV and other respiratory viruses.
resultsOf all cases, HBoV was detected in 10.0%, with a peak incidence of infection among children < 2 year old, and predominantly noted in autumn and winter. Only 8 patients were HBoV single infection. Co-infection with other respiratory viruses was observed in 86.4%. Moreover, co-infection with bacteria occurred in 27.3% and with Mycoplasma pneumoniae (MP) in 33.0% of HBoV-positive patients. Among all HBoV-positive samples co-infected with bacteria, 87.5% are gram negative bacteria. Compared with HBoV-negative group, age (P = 0.048), wheezing (P = 0.015), tachypnea (P = 0.016), lactate dehydrogenase (P = 0.026) and severe pneumonia (P = 0.023) were statistically significant in HBoV-positive patients. Furthermore, HBoV-positive patients less than 1 year old were more likely to have co-infection with bacteria (P = 0.007).
conclusionsHBoV can be detected alone in respiratory samples of children with CAP, maybe it is one of the causes of CAP in infants. The high incidence of severe pneumonia was found in HBoV-positive patients compared with HBoV-negative cases may indicate a relationship between severe pneumonia and HBoV.
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