Evidence map›Paper›PMID 34715814›Full record

ArticleBMC infectious diseases2021

Comparison of clinical manifestation of dengue fever in Bangladesh: an observation over a decade.

Mohammad Jahid Hasan, Tamanna Tabassum, Mohiuddin Sharif, Md Abdullah Saeed Khan, Akhi Roy Bipasha, Ariful Basher, Mohammad Rafiqul Islam, Mohammad Robed Amin

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Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Epidemiological Characteristics of Dengue Infection in Bangladesh: A Systematic Review.International journal of environmental research and public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammad Jahid HasanPi Research Consultancy Center, Dhaka, Bangladesh. dr.jahid61@gmail.com.ORCID http://orcid.org/0000-0001-9212-1739
Tamanna TabassumPi Research Consultancy Center, Dhaka, Bangladesh.
Mohiuddin SharifDepartment of Medicine, Dhaka Medical College and Hospital-2, Dhaka, Bangladesh.
Md Abdullah Saeed KhanPi Research Consultancy Center, Dhaka, Bangladesh.
Akhi Roy BipashaPi Research Consultancy Center, Dhaka, Bangladesh.
Ariful BasherBSMMU, OSD, Directorate General of Health Service, Dhaka, Bangladesh.
Mohammad Rafiqul IslamDepartment of Medicine, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh.
Mohammad Robed AminDepartment of Medicine, Dhaka Medical College and Hospital-2, Dhaka, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical presentation of dengue fever had been observed to change with time since its first outbreak in 2000 in Bangladesh. This report showed the clinical presentation of the 2019 outbreak in Bangladesh along with its comparison to previous outbreaks witnessed in this region.

methodsThis hospital-based cross-sectional study was conducted in one of the largest tertiary care hospitals in Dhaka city. A total of 553 laboratory-confirmed and 194 probable dengue cases were interviewed. The clinical manifestation of the confirmed cases of the current outbreak was compared with three of the outbreak reports retrieved from the databases. R version 3.6.3 was used for data analysis.

resultsAmong the confirmed cases, two-thirds were male (63.2%) and the average age was 27(± 11) years. Positive tests for NS1 and IgM were present in 99.6% (n = 525/527) and 82.6% (n = 38/46) of the cases, respectively. Thrombocytopenia was present in 66.1% of cases. Fever (100%) was common for all. Gastrointestinal (GIT) features, including abdominal pain (86.5%), anorexia and/or vomiting (69.6%), and Diarrhea (> 3 motions/day) (26.2%) were more frequent than typical rash and other pain symptoms. Hypotension was present in approximately a quarter of patients (25%). GIT features (anorexia, nausea, and/or vomiting) and hypotension were more common among adult participants while bleeding manifestation (melena and vaginal bleeding, p = 0.009 & 0.032) was more frequent in pediatric patients. Compared to outbreaks of 2008, 2016, and 2018, increasing trends in GIT symptoms e.g. anorexia, abdominal pain, and diarrhea were observed. While a negative trend in hemorrhagic manifestations (skin rash, melena, and conjunctival hemorrhage/hemorrhagic sclera) and arthralgia/joint pain were found.

conclusionThe present outbreak was noticeably characterized by GIT symptoms and hypotension in addition to the typical clinical features like rash and pain symptoms. An increasing trend in GIT features and decreasing trend in hemorrhagic manifestations was noted over the last decade of dengue outbreaks.

Indexed as

DengueDisease OutbreaksAdolescentAdultBangladeshChildCross-Sectional StudiesFemaleFeverHumansMaleYoung AdultDengue feverDengue hemorrhagic feverDengue outbreakDengue shock syndromeShift of paradigm

Identifiers

PMID34715814
PMCPMC8555248

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.