ArticleBMC microbiology2021
Genomic convergence between Akkermansia muciniphila in different mammalian hosts.
Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Akkermansia muciniphila : A next-generation gut probiotic supporting neurorepair and functional recovery.Neural regeneration research · 2026Article
- Gut microbiota and immune modulation: role in neurodegenerative disorders and cancer.Molecular biology reports · 2026Review
- A molecular inventory of the faecal microbiomes of 23 marsupial species.Microbial genomics · 2026Article
- The genus Akkermansia is populated by a multitude of biological species with a wide distribution in the animal kingdom.Biology direct · 2025Article
- Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential.Nature reviews. Microbiology · 2025Review
- Symbiotic strategies: deciphering the role of gut microbiota in the nutrition and metabolism of fish and shellfish.Frontiers in cellular and infection microbiology · 2025Review
- The worldview ofFrontiers in microbiology · 2025Review
- Social behaviour mediates the microbiome response to antibiotic treatment in a wild mammal.Proceedings. Biological sciences · 2024Article
- Whole-genome sequencing and genomic analysis of fourFrontiers in microbiology · 2024Article
- Article
- Gut Microbiome-Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders.ACS chemical neuroscience · 2023Review
- Akkermansia muciniphila exerts immunomodulatory and anti-inflammatory effects on gliadin-stimulated THP-1 derived macrophages.Scientific reports · 2023Article
- Mode of action ofMicrobiome research reports · 2023Review
- Health and Disease:Research (Washington, D.C.) · 2023Article
- Insights into early evolutionary adaptations of theFrontiers in microbiology · 2023Article
- Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms.Nature reviews. Gastroenterology & hepatology · 2022Review
- Comparative Genomics and Physiology ofMicroorganisms · 2022Article
- Revisiting the role ofGut microbesArticle
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAkkermansia muciniphila is a member of the human gut microbiota where it resides in the mucus layer and uses mucin as the sole carbon, nitrogen and energy source. A. muciniphila is the only representative of the Verrucomicrobia phylum in the human gut. However, A. muciniphila 16S rRNA gene sequences have also been found in the intestines of many vertebrates.
resultsWe detected A. muciniphila-like bacteria in the intestines of animals belonging to 15 out of 16 mammalian orders. In addition, other species belonging to the Verrucomicrobia phylum were detected in fecal samples. We isolated 10 new A. muciniphila strains from the feces of chimpanzee, siamang, mouse, pig, reindeer, horse and elephant. The physiology and genome of these strains were highly similar in comparison to the type strain A. muciniphila Muc
conclusionsThe low genomic divergence observed in the new strains may indicate that A. muciniphila favors mucosal colonization independent of the differences in hosts. In addition, the conserved mucus degradation capability points towards a similar beneficial role of the new strains in regulating host metabolic health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.