Evidence map›Paper›PMID 34715752›Full record

ArticleThe International journal of artificial organs2022

Effects of the atrium on intraventricular flow patterns during mechanical circulatory support.

Mojgan Ghodrati, Thomas Schlöglhofer, Alexander Maurer, Thananya Khienwad, Daniel Zimpfer, Dietrich Beitzke, Francesco Zonta, Francesco Moscato, Heinrich Schima, Philipp Aigner

Abstract read
In one paragraph

Article in The International journal of artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mojgan GhodratiCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Thomas SchlöglhoferCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Alexander MaurerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Thananya KhienwadCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Daniel ZimpferDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Dietrich BeitzkeDepartment of Biomedical Imaging and Image guided Therapy, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-3179-3827
Francesco ZontaInstitute of Fluid Dynamics and Heat Transfer, Technical University of Vienna, Vienna, Austria.
Francesco MoscatoCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Heinrich SchimaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Philipp AignerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-3212-2112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simulations of the ventricular flow patterns during left ventricular assist device (LVAD) support are mainly performed with idealized cylindrical inflow, neglecting the influence of the atrial vortex. In this study, the influence of the left atrium (LA) on the intra-ventricular flow was investigated via Computational Fluid Dynamics (CFD) simulations. Ventricular flow was simulated by a combined Eulerian (carrier flow)/Lagrangian (particles) approach taking into account either the LA or a cylindrical inflow section to mimic a fully support condition. The flow deviation at the mitral valve, the blood low-velocity volume as well as the residence time and shear stress history of the particles were calculated. Inclusion of the LA deflects the flow at the mitral valve by 25°, resulting in an asymmetric flow jet entering the left ventricle. This reduced the ventricular low-velocity volume by 40% (from 6.4 to 3.9 cm

Indexed as

Heart-Assist DevicesModels, CardiovascularBlood Flow VelocityComputer SimulationHeart AtriaHeart VentriclesHemodynamicscomputational fluid dynamicsintraventricular flow patternleft atriumLeft ventricle assist deviceresidence timeshear stress history

Identifiers

PMID34715752
PMCPMC8922056

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.