ArticleJournal of clinical epidemiology2022
Estimating total morbidity burden of COVID-19: relative importance of death and disability.
Article in Journal of clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Measured and Perceived Effects of Upper Limb Home-Based Exergaming Interventions on Activity after Stroke: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Long COVID disability burden in US adults.Communications medicine · 2026Article
- Reframing disease burden: validation of DALY-per-case as a per-diagnosis severity metric.Population health metrics · 2026Article
- Article
- Post-Coronavirus Disease 2019 Effects in an Active University Population: A Within-Campus Cross-Sectional Study at a Major Educational Institution.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024Article
- Rehabilitative interventions in patients with persistent post COVID-19 symptoms-a review of recent advances and future perspectives.European archives of psychiatry and clinical neuroscience · 2024Review
- Clinical and functional assessment of SARS-CoV-2 sequelae among young marines - a panel study.Lancet regional health. Americas · 2024Article
- Long COVID Prevalence, Disability, and Accommodations: Analysis Across Demographic Groups.Journal of occupational rehabilitation · 2024Article
- Projecting the long-term effects of the COVID-19 pandemic on U.S. population structure.Nature communications · 2024Article
- Inequalities in healthcare use during the COVID-19 pandemic.Nature communications · 2024Article
- Fatigue, sleepiness and sleep quality are SARS-CoV-2 variant independent in patients with long COVID symptoms.Inflammopharmacology · 2023Review
- Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome.Brain sciences · 2023Article
- Article
- The health impact of long COVID during the 2021-2022 Omicron wave in Australia: a quantitative burden of disease study.International journal of epidemiology · 2023Article
- Leadership and contagion by COVID-19 among residence hall students: A social network analysis approach.Social networks · 2023Article
- Burden of COVID-19 disease in Kurdistan province in west of Iran using disability-adjusted life years.Health science reports · 2023Article
- Review
- Comprehensively identifying Long Covid articles with human-in-the-loop machine learning.Patterns (New York, N.Y.) · 2023Article
- Direct impact of COVID-19 by estimating disability-adjusted life years at national level in France in 2020.PloS one · 2023Article
- Association between long COVID and vaccination: A 12-month follow-up study in a low- to middle-income country.PloS one · 2023Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCalculations of disease burden of COVID-19, used to allocate scarce resources, have historically considered only mortality. However, survivors often develop postinfectious 'long-COVID' similar to chronic fatigue syndrome; physical sequelae such as heart damage, or both. This paper quantifies relative contributions of acute case fatality, delayed case fatality, and disability to total morbidity per COVID-19 case. STUDY DESIGN AND
settingHealthy life years lost per COVID-19 case were computed as the sum of (incidence*disability weight*duration) for death and long-COVID by sex and 10-year age category in three plausible scenarios.
resultsIn all models, acute mortality was only a small share of total morbidity. For lifelong moderate symptoms, healthy years lost per COVID-19 case ranged from 0.92 (male in his 30s) to 5.71 (girl under 10) and were 3.5 and 3.6 for the oldest females and males. At higher symptom severities, young people and females bore larger shares of morbidity; if survivors' later mortality increased, morbidity increased most in young people of both sexes.
conclusionsUnder most conditions most COVID-19 morbidity was in survivors. Future research should investigate incidence, risk factors, and clinical course of long-COVID to elucidate total disease burden, and decisionmakers should allocate scarce resources to minimize total morbidity.
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