ArticleBiophysical journal2021
Contact pairs of RNA with magnesium ions-electrostatics beyond the Poisson-Boltzmann equation.
Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Alteration of the Lipid Bilayer Structure by MgLangmuir : the ACS journal of surfaces and colloids · 2026Article
- Influence of MgACS omega · 2023Article
- Rolling circle RNA synthesis catalyzed by RNA.eLife · 2022Article
- The mutual interactions of RNA, counterions and water - quantifying the electrostatics at the phosphate-water interface.Chemical communications (Cambridge, England) · 2021Review
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
The electrostatic interaction of RNA with its aqueous environment is most relevant for defining macromolecular structure and biological function. The attractive interaction of phosphate groups in the RNA backbone with ions in the water environment leads to the accumulation of positively charged ions in the first few hydration layers around RNA. Electrostatics of this ion atmosphere and the resulting ion concentration profiles have been described by solutions of the nonlinear Poisson-Boltzmann equation and atomistic molecular dynamics (MD) simulations. Much less is known on contact pairs of RNA phosphate groups with ions at the RNA surface, regarding their abundance, molecular geometry, and role in defining RNA structure. Here, we present a combined theoretical and experimental study of interactions of a short RNA duplex with magnesium (Mg
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